Background: Lichen planus is a common inflammatory disease that can involve the skin, nails, mucous membrane, and hair follicles. There is a long list of topical and systemic therapies for its treatment. Methotrexarte has some characteristics that make it a good choice for generalized lichen planus. Aim: The goal of this study was to assess the effect of low dose methotrexate in generalized lic...

Sir, oral mucosal as well as skin lesions had a good response. One patient with oral mucosal lesions along with generalized skin Lichen planus is usually a benign and self-limiting disease but in some patients the disease may be severe and unremitting, involvement had a poor response (40%) to the therapy. This patient took the drug for 3 months only and did not report requiring therapeutic inte...

FDG: fluorodeoxyglucose LPP: lichen planopilaris PET-CT: positron emission tomographye computed tomography PD-1: programmed cell death receptor 1 P embrolizumab, a programmed cell death receptor 1 (PD-1) inhibitor, has been used effectively for treatment of metastatic melanoma. Reported cutaneous adverse events ascribed to PD-1 inhibitors include lichenoid reactions such as lichen planus of the...

statement of the problem: lichen planus is a mucocutaneous disease that is relatively common in middle aged individuals. some studies have shown that oral lichen planus has a potential to progress to squamous cell carcinoma.p21 is a cyclin-dependent kinase inhibitor that regulates the cell cycle, thus it acts as an inhibitor in cell proliferation. purpose: this study was aimed to evaluate and c...

1. Tilly JJ, Drolet BA, Esterly NB. Lichenoid eruptions in children. J Am Acad Dermatol. 2004;51:606-24. 2. Aloi F, Solaroli C, Pippione M. Diffuse and bilateral lichen striatus. Pediatr Dermatol. 1997;14:36-8. 3. Mittal R, Khaitan BK, Ramam M, Verma KK, Manchanda M. Multiple lichen striatus-An unusual presentation. Indian J Dermatol Venereol Leprol. 2001;67:204. 4. Peramiquel L, Baselga E, Dal...

Although lichen planus is a fairly common disorder, its familial occurrence is uncommon and varies between 1.5 and 10.7%. In most reports, only two or three members of the family have had disease but occasionally more family members may be affected. We present a case of lichen planus, whose father, mother, and maternal aunt also had this disease.

background and aims. oral lichen planus (olp) is a common chronic mucocutaneous disease. patients with atrophic and erosive lichen planus often have symptoms of soreness and need proper treatment. the main therapy of olp has been the administration of topical or systemic corticosteroids. potent topical corticosteroids have been increasingly prescribed in the treatment of erosive lichen planus. ...