Polymer microarrays are a key enabling technology for the discovery of novel materials. This technology can be further enhanced by expanding the combinatorial space represented on an array. However, not all materials are compatible with the microarray format and materials must be screened to assess their suitability with the microarray manufacturing methodology prior to their inclusion in a mat...

A novel approach is presented for manipulating the size and chemistry of nanoscopic features using a combination of contact molding and living free radical polymerization. In this approach a highly cross-linked photopolymer, based on a methacrylate/acrylate mixture, was patterned into submicrometer-sized features on a silicon wafer using a contact-molding technique. A critical component of the ...

Polymer microarrays are a key enabling technology for the discovery of novel materials. This technology can be further enhanced by expanding the combinatorial space represented on an array. However, not all materials are compatible with the microarray format and materials must be screened to assess their suitability with the microarray manufacturing methodology prior to their inclusion in a mat...

Trimethoprim-MIPs were prepared by using (TMP) as the template well allylchloride (AYC) or allylbromide (AYB) monomer, used (TMPTA) tri methylol propane acrylate ethylene glycol di methyl (EGDMA) cross-linker and initiator (BP) benzyl peroxide. By different plasticizers (di butyl Phthalate (DBPH), Nitrobenzene (NB), oleic acid (OA) paraffin) for TMP-MIP1 (Di sebecate (DBS), Di (DMA), Tributylph...

We have been engaged in a search for coordination catalysts for the copolymerization of polar monomers (such as vinyl chloride and vinyl acetate) with ethylene. We have been investigating complexes of late transition metals with heterocyclic ligands. In this report we describe the synthesis of a symmetrical bis-thiadiazole. We have characterized one of the intermediates using single crystal X-r...

Statistical copolymer films that consist of two types of monomers, a sticky and a glassy monomer, are investigated. These model systems of pressure-sensitive adhesive films are probed with X-ray reflectivity and mechanical tack measurements. For the first time, composition profiles along the surface normal in the near-surface region are monitored. The influence of the type of monomers being cop...

From the standpoint of the mechanism of mechanochemical polymerization, two kinds of copolymeric prodrug, whose monomer sequence distribution (MSD) is different from each other, can be prepared by this polymerization under appropriate operational conditions: one is a random copolymer abundant in the longer block consisting of the same repeating units (multi-block copolymer), and the other is a ...

The Escherichia coli YhdH polypeptide is in the MDR012 sub-group of medium chain reductase/dehydrogenases, but its biological function was unknown and no phenotypes of YhdH(-) mutants had been described. We found that an E. coli strain with an insertional mutation in yhdH was hyper-sensitive to inhibitory effects of acrylate, and, to a lesser extent, to those of 3-hydroxypropionate. Close homol...