776 CMAJ, April 19, 2011, 183(7) © 2011 Canadian Medical Association or its licensors Iwish I could have been in Banting’s audience when he addressed the Canadian Medical Association in June 1926. I suspect that there would have been few women present, and I wonder what the audience made of the youthful speaker with his already extraordinarily distinguished resumé. The text of the lecture was p...

Exfoliation is the process of removal of removing the old, dead skin cells that cling to the skin’s outermost surface. The two types of exfoliation are mechanical and chemical. People’s opportunities for seeking dermatological assistance for a myriad of conditions, including acne, rosacea, striae, photodamage, and skin cancers have increased in recent years. Chronological aging is a process of ...

BACKGROUND Unlike T-cell neoplasms, B-cell lymphoproliferative disorders have a limited clinical spectrum of skin involvement. Cutaneous B-cell neoplasms mimicking rosacea or rhinophyma are rare. OBSERVATIONS We described 12 patients with B-cell lymphoproliferative neoplasms presenting with a facial eruption clinically mimicking rosacea or rhinophyma. Eleven patients were women; ages ranged f...

Pathophysiology Rosacea results from an inflammatory process about which little is known. The stimulus includes a wide variety of foods as well as environmental, chemical, psychologic, and emotional factors (Table 1). It is unclear what role, if any, these factors have in the causation or exacerbation of this condition. In particular, the link between emotional stress and rosacea is not well un...

Rosacea is a chronic inflammatory disease of the skin mainly central facial region, having gender and age correlations. Currently, more data accumulating on analysis rosacea phenotypes, scientific discussions are underway feasibility switching from subtype classification to phenotypic justify individualized approaches therapy. The based manifestations distinguishes diagnostic signs main seconda...

The pathophysiology of the vascular and inflammatory stages of facial rosacea and proposes an underlying cause is reviewed. It can be argued that all the stigmata of rosacea are manifestations of an inflammatory process: neutrophilic dermatosis. For this reason, treatments that block neutrophil involvement in the development of rosacea, such as topical metronidazole and systemic antibodies, sho...

Rosacea is one of the most common conditions dermatologists treat. Rosacea is most often characterized by transient or persistent central facial erythema, visible blood vessels, and often papules and pustules. Based on patterns of physical findings, rosacea can be classified into 4 broad subtypes: erythematotelangiectatic, papulopustular, phymatous, and ocular. The cause of rosacea remains some...

Rosacea is a chronic inflammatory condition of the facial skin affecting the blood vessels and pilosebaceous units. Rosacea is more common in persons of northern and western European descent with a fair complexion, but it can affect skin of any color. Although symptoms may wax and wane during the short term, rosacea can progress with time. Patients usually present with complaints of flushing an...

Rosacea is a condition of vasomotor instability characterized by a facial erythema most notable in the central convex areas of the face and by remission and exacerbations (1, 2). Several clinical entities within the diagnosis have been described in adults: erythematoteleangiectatic, papulopustular, phymatous and ocular (3). Rosacea is a common chronic dermatological condition in adults. It has ...

The SQUAMOSA promoter binding protein (SBP)-box proteins are plant-specific transcriptional factors in plants. SBP TFs are known to play important functions in a diverse development process and also related in the process of evolutionary novelties. SBP gene family has been characterized in several plant species, but little is known about molecular evolution, functional divergence and comprehens...