Hetaryl-substituted thiochalcones react with acetylenic monoand diesters in the THF solution in the presence of LiClO4 at 65°C to give, after 24h, 4H-thiopyran carboxylates and dicarboxylates, respectively, in moderate to good yields. The same reactions were performed also in the THF solution without a catalyst under microwave irradiation. In that case, the reaction time was reduced to three mi...

protonation of the reactive intermediates generated in the raction between dalkyl acetylenedicarboxylates and triphenylphosphine by isonitrosoacetophenone leads to vinyltriphenylphosphonium salts, which undergo intramolecular wittig reaction to produce dalkyl 4-phenyl-n-hydroxypyrrole-2,3-dicarboxylates in moderate yields.

Encapsulated anticorrosion agents provide a suitable alternative to dispersion of metal-based compounds in protective polymeric coatings on metal substrates. Stimuli-responsive microcapsules enhance protection abilities by autonomously responding corrosion-induced environmental changes, rather than relying damage-induced mechanical stimuli. This work reports pH-responsive with triggered release...

CLICK SCAFFOLDS FOR THE INHIBITION OF PORPHYROMONAS GINGIVALIS AND STREPTOCOCCUS GORDONll BIOFILM FORMATION Catherine M. Loner April 18,2012 Periodontitis and its systemic sequelae remain a major public health problem and developing a cost-efficient therapy will benefit healthcare worldwide. Adherence of Porphyromonas gingivalis to Streptococcus gordonii facilitates colonization ofthe oral cavi...