Previous investigators (Frawley, Hagan & Fitzhugh, 1952; Davison, 1955; Kewitz & Nachmansohn, 1957) have observed that the rate of recovery in vivo of inhibited brain true cholinesterase depended on which inhibitor was used. With diiwopropyl phosphorofluoridate (Frawley et al. 1952; Davison, 1955; Kewitz & Nachmansobn, 1957) recovery was slow, whereas with tetraethyl pyrophosphate (Davison, 195...

Dementia is one of the age related mental problems and a characteristic symptom of various neurodegenerative disorders including Alzheimer’s disease. Desmodium gangeticum DC. (Leguminosae) is widely used in Ayurveda for treating various neurological disorders. In the present study, the effectiveness of aqueous extract of D. gangeticum in attenuating scopolamine-induced amnesia in mice was inves...

The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...

BACKGROUND Farmworkers can be exposed to a wide variety of pesticides. Assessing cholinesterase activity over time can be used to monitor exposure to organophosphorus and carbamate pesticides. OBJECTIVES The goal of this study was to document patterns and variation in cholinesterase levels across the agricultural season (May-August) among field-workers, and to explore the association of choli...

STUDY OBJECTIVE To evaluate the usefulness of two new parameters for separating pleural transudates and exudates: pleural fluid cholinesterase level and pleural fluid to serum cholinesterase ratio, and to compare the results with the other well-established criteria. DESIGN Prospective evaluation of the patients referred for diagnostic thoracentesis. SETTING Pulmonary sections of a community...

A histochemical staining technique for cholinesterase is reported for the study of corneal nerves in whole-thickness rabbit cornea. The technique is relatively simple, yields reproducible results, allows good definition of the nerve fiber pattern, and provides the investigator, using a binocular microscope, with the advantage of three-dimensional study. When tissue is stained for specific choli...

Fifteen patients demonstrating unexpected prolonged apnoea lasting several hours after succinylcholine have been treated by a new preparation of human serum cholinesterase. Adequate spontaneous respiration was re-established in an average period of ten minutes after the injection. In 12 patients biochemical genetic examinations confirmed the presence of an atypical serum cholinesterase. In thre...

the aim of this study was to investigate the effect of 8 weeks of endurance and resistance training on the activity of g4 acetyl cholinesterase in fhl and soleus muscles of rats. 24 male wistar rats (age: 10 weeks and weight: 171.94±8.961 gr) were randomly divided into 3 groups (control, endurance training (et) and resistance training (rt)). et and rt groups carried out 8 weeks (5 sessions per ...