A mild and efficient one-pot protocol to selectively remove N-acetyl groups, subsequently functionalize the generated amines, is reported. Common functional such as esters, carbamates thioglycosides, are tolerated.

The fungus Alternaria tenuis normally produces tenuazonic acid (3-acetyl-5-secbutyltetramic acid). On supplementation of the culture substrate with l-valine and l-leucine, the organism formed two new tetramic acids, 3-acetyl-5-isopropyltetramic acid and 3-acetyl-5-isobutyltetramic acid, respectively. l-Phenylalanine was not utilized by the organism as a tetramic acid precursor.

The specific capsular polysaccharide of type 46 Streptococcus pneumoniae (American type 73) was isolated in pure form and shown to be a high-molecular-weight, glycosidically linked polymer composed of d-galactose (2 mol), N-acetyl-d-glucosamine (1 mol), N-acetyl-d-galactosamine (1 mol), and N-acetyl-l-fucosamine (1 mol).

Three new cycloartane triterpene glycosides, soulieosides A (1), B (2), and C (3), were isolated from the rhizomes of Souliea vaginata, and their structures were elucidated on the basis of extensive NMR experiments and chemical methods. Soulieosides A-C were assigned as 25-O-acetylcimigenol-3-O-beta-D-(2-acetyl)xylopyranoside (1), 24-O-acetyl-isodahurinol-3-O-beta-D-(2-acetyl)xylopyranoside (2)...

This paper reports the synthesis and characterization of monomers itaconic anhydride (IA) tri-O-acetyl-D-glucal (TAG) as well 4,6-di-O- -acetyl-D-glucal (PSG). The homopolymers copolymers IA TAG were synthesized via free radical copolymerization in bulk, using azobisisobutyronitrile an initiator with different feed ratios monomers. Their structural, molecular thermal was done 1H-NMR spectroscop...

As the major lysosomal degradation pathway, autophagy represents the guardian of cellular homeostasis, removing damaged and potentially harmful material and replenishing energy reserves in conditions of starvation. Given its vast physiological importance, autophagy is crucially involved in the process of aging and associated pathologies. Although the regulation of autophagy strongly depends on ...

An esterase which is encoded within a Thermotoga maritima chromosomal gene cluster for xylan degradation and utilization was characterized after heterologous expression of the corresponding gene in Escherichia coli and purification of the enzyme. The enzyme, designated AxeA, shares amino acid sequence similarity and its broad substrate specificity with the acetyl xylan esterase from Bacillus pu...

In the mol-ecule of the title compound, C(7)H(15)N(3)O, the central C atom is surrounded in a nearly ideal trigonal-planar geometry by three N atoms. The C-N bond lengths in the CN(3) unit are 1.3353 (13), 1.3463 (12) and 1.3541 (13) Å, indicating an inter-mediate character between a single and a double bond for each C-N bond. The bonds between the N atoms and the terminal C-methyl groups all h...

We present the strategic development of a synthetic onepot two-step process for manufacture acetyl-protected hydroxystyrenes from phenolic acid substrates using environmentally benign (bio)catalysts in an eco-friendly solvent.

Sulfate-reducing bacteria (SRB) in anoxic waters and sediments are the major producers of methylmercury in aquatic systems. Although a considerable amount of work has addressed the environmental factors that control methylmercury formation and the conditions that control bioavailability of inorganic mercury to SRB, little work has been undertaken analyzing the biochemical mechanism of methylmer...