introduction: hypoparathyroidism (hpt) is an irreversible but preventable disorder caused by an iron overload which can be considered a typical complication in patients with beta-thalassemia major. patients and method: parathyroid function was evaluated in 130 patients in qom, iran, who suffered from beta-thalassemia major. their serum ferritin levels were checked for monitoring of chelation th...

BACKGROUND Clinical practice guidelines recommend ad hoc screening of diabetes in patients admitted for macrovascular disease; however, these recommendations are rarely followed in real practice. This study was undertaken to assess whether impaired glucose metabolism, newly diagnosed after percutaneous coronary intervention (PCI) or known diabetes, provides prognostic information. METHODS We ...

Background: Diabetes Mellitus is a heterogeneous group of different metabolic disorders that are characterized by chronic increase of blood glucose, cardiovascular diseases, and proteins, lipids and carbohydrate metabolism disorder. Leptin, that is a marker of fat mass in the body, has an important role in the body total metabolism and glucose homeostasis. Aim: To investigate the effect of 12 w...

conclusions we observed no significant differences between the two groups in lipid and carbohydrate metabolism, except for hdl-c. considering the importance of overweight and obese women’s health, studies with longer follow-up periods are recommended in this respect. results the differences in lipid and carbohydrate parameters were not significant between the two groups, except for hdl-c (adjus...

Chronic lymphocytic leukemia (CLL) remains fatal due to the development of resistance to existing therapies. Targeting abnormal glucose metabolism sensitizes various cancer cells to chemotherapy and/or elicits toxicity. Examination of glucose dependency in CLL demonstrated variable sensitivity to glucose deprivation. Further evaluation of metabolic dependencies of CLL cells resistant to glucose...

After a carbohydrate-containing meal, the liver maintains plasma glucose concentration within a narrow range by taking up onequarter to one-third of the absorbed glucose, oxidizing some of it and storing the rest as glycogen or converting it into fat. In the postabsorptive state, the liver provides much needed glucose to the central nervous system and other glucose-utilizing tissues by breaking...