background: laparoscopic ovarian drilling (lod) is an alternative method to induce ovulation in polycystic ovary syndrome (pcos) patients with clomiphene citrate (cc) resistant instead of gonadotropins. this study aimed to compare the efficacy of unilateral lod (ulod) versus bilateral lod (blod) in cc resistance pcos patients in terms of ovulation and pregnancy rates. materials and methods: in ...

Infertility is defined as failure to achieve pregnancy during one year of frequent, unprotected intercourse. Evaluation generally begins after 12 months, but it can be initiated earlier if infertility is suspected based on history or if the female partner is older than 35 years. Major causes of infertility include male factors, ovarian dysfunction, tubal disease, endometriosis, and uterine or c...

BACKGROUND This study was aimed to assess the effect of endometrial movements on pregnancy achievement in intrauterine insemination (IUI) cycles. MATERIALS AND METHODS The population of this observational study was composed of unexplained infertility couples undergoing first-time IUI with clomiphene citrate between September 2010 and October 2011. Not only endometrial movements, but also thic...

BACKGROUND The aim of this randomized controlled trial was to compare the efficacy of extended letrozole regimen with clomiphene citrate in women with unexplained infertility undergoing superovulation and intrauterine insemination (IUI). METHODS Two hundred and fourteen patients with unexplained infertility were randomized into two equal groups using computer generated list and were treated b...

OBJECTIVE The objective of this study is to develop and characterize in situ thermosensitive gels for the vaginal administration of sildenafil as a potential treatment of endometrial thinning occurring as a result of using clomiphene citrate for ovulation induction in women with type II eugonadotrophic anovulation. While sildenafil has shown promising results in the treatment of infertility in ...

background: intracytoplasmic sperm injection (icsi) is an advanced technique employed in assisted reproductive clinics for treatment of infertile couples. the reproductive endocrinologists try their level best to identify factors that enhance success rate after icsi. objective: to compare estradiol progesterone ratio on ovulation induction day amongst pregnancy outcome groups following icsi. ma...

AIM The objective of this study was to compare the use of clomiphene citrate and letrozole in an IVF setting in which the objective was to produce only one or two embryos. Either clomiphene citrate or letrozole was used in conjunction with gonadotropins without the use of GnRH antagonists. METHODS Sixty-two patients received either clomiphene citrate or letrozole with low dose gonadotropins i...

PURPOSE To evaluate the pregnancy rate in intrauterine insemination (IUI), and to determine possible prognostic factors of successful pregnancy. METHODS A retrospective study of IUI cycles performed in the Reproductive Medicine Unit of Vila Nova de Gaia Hospital, between January 2007 and July 2010. The IUI cycles were preceded by ovarian stimulation and monitored by vaginal ultrasound. Clinic...

Objective: To investigate the effect of adding metformin to clomiphene citrate (CC) in polycystic ovarian syndrome (PCOS) patients with acanthosis nigricans (AN) who were previously not responding to CC. Material and Methods: A double blinded randomized controlled trial (NCT02562664) included 66 PCOS women with acanthosis nigricans who were CC resistant (at least 3 months). Day 3 follicle stimu...

INTRODUCTION Heterotopic pregnancy is a life-threatening complication of pregnancy defined as coexistent intrauterine and ectopic gestation. Its diagnosis is frequently overlooked and delayed. CASE OUTLINE A 28-year-old woman experienced acute abdominal pain in pregnancy achieved by in vitro fertilization. Since all previous checkups indicated a normal course of pregnancy, the ectopic pregnan...