Natural products are the major sources of currently available anticancer drugs. We recently reported that phenanthrene-based tylophorine derivative-1 (PBT-1) may be a potential antitumor agent for lung adenocarcinoma. We therefore examined the direct targets of PBT-1 and their effects in inhibiting lung adenocarcinoma. We found that PBT-1 reduced the level of Slug and inhibits the migration, in...

Climate change would significantly affect the temporal pattern and amount of annual precipitation at the regional level, which in turn would affect the regional water resources and future water availability. The Peace Region is a critical region for northern British Columbia’s social, environmental, and economic development, due to its potential in various land use activities. This study invest...

The notation and terminology used in this paper are introduced in the following papers: [12], [11], [14], [7], [8], [6], [9], [16], [2], [3], [1], [13], and [4]. Let X be a set and let Y be a subset of 2 . Then ⋃ Y is a subset of X. In this article we present several logical schemes. The scheme DenestFraenkel concerns a non empty set A, a non empty set B, a unary functor F yielding arbitrary, a...

On global scale, community participation in various activities is the core in the quest for sustainable development and environmental protection related issues. Community involvement in tree planting in Kenya is as old as modern agroforestry that started in 1971. However, certain biophysical environmental factors have not worked against the concept of community participation in tree planting. A...

Spectra of ã B1(n1n2n3)5(110) and (200) – X̃ A1(000) of SO2 and SO2 are obtained in a supersonic jet at a resolution 0.015 cm. The rotational structures are analyzed for both isotopic species to obtain precise rotational and spin constants. Two new bands at 27 032.222~1! and 27 515.41~1! cm arising from vibronic interaction separately with vibrational state ~110! and ~200! of ã B1 are assigned t...

hnRNP A2/B1 has been suggested as a useful early detection marker for lung carcinoma. hnRNP A2/B1 is a member of a large family of heterogeneous nuclear ribonucleoproteins (hnRNP proteins) involved in a variety of functions, including regulation of transcription, mRNA metabolism, and translation. In lung cancer, we have evaluated the expression and cellular localization of several members of th...

Proteolytic fungi from the soil samples were isolated on Reese agar plate containing casein as the protein substrate. The mycoflora of different localities of Sagar and Jabalpur districts of Madhya Pradesh were investigated at three different locations viz. Garden, Crop field and Poultry farms. These samples were labeled according to the site of collection as GS (Garden Soil), CFS (Crop Field S...

Recently, Zhu [34] introduced a Stirling-Whitney-Riordan triangle [Tn,k]n,k?0 satisfying the recurrence Tn,k = (b1k + b2)Tn?1,k?1 [(2?b1 a1)k a2 ?(b1 b2)]Tn?1,k ?(a1 ?b1)(k 1)Tn?1,k+1, where initial conditions 0 unless ? k n and T0,0 1. Denote by Tn Pnk =0 Tn,k. In this paper, we show asymptotic normality of give an formula Tn. As applications, many famous combinatorial numbers, such as Stirlin...

Rate and Method of Application Apply as a preplant broadcast treatment at least 14 to 21 days prior to planting. Late summer or early autumn is usually best for applying soil fumigants in Michigan. Inject 8 inches deep with chisels spaced 10 to 12 inches apart when soil temperature is between 50° and 80°F. Seal immediately after application. If soil is waterlogged or temperature is below 60°F, ...

The Japanese randomized trial comparing standard D2 with D2 plus additional para-aortic lymph node (PAN) dissection for advanced gastric cancer (JCOG study 9501) did not demonstrate any difference in survival between the two groups. It is unknown whether there is any prognostic benefit in dissection for subgroups of PAN. Non-inferiority in survival of the patients with PAN metastasis to the pat...