tRNA genes are interspersed throughout eukaryotic DNA, contributing to genome architecture and evolution in addition to translation of the transcriptome. Codon use correlates with tRNA gene copy number in noncomplex organisms including yeasts. Synonymous codons impact translation with various outcomes, dependent on relative tRNA abundances. Availability of whole-genome sequences allowed us to e...

A series of phosphine-ligated palladium precatalysts based on N-methyl- and N-phenyl-2-aminobiphenyl have been developed. Substitution at the nitrogen center prevents the presence of traces of aminobiphenyls that contain a free -NH2 group from contaminating cross-coupling products. These precatalysts produce N-substituted carbazoles upon activation, which cannot consume starting materials. Thes...

Background Xyloglucan (XyG) is a ubiquitous and fundamental polysaccharide of plant cell walls. Due to its structural complexity, XyG requires a combination of backbone-cleaving and sidechain-debranching enzymes for complete deconstruction into its component monosaccharides. The soil saprophyte Cellvibrio japonicus has emerged as a genetically tractable model system to study biomass saccharific...

BACKGROUND AND AIMS Lake Biwa is one of the world's few ancient lakes. Formed ∼4 million years ago, the lake harbours many coastal species that commonly inhabit seashores. The beach pea Lathyrus japonicus is a typical coastal species of this freshwater lake, but its inland populations are faced with the threat of extinction. Here, we investigated the phylogeographical and population structures ...

Chub mackerel (Scomber japonicus Houttuyn, 1782) were obtained from the commercial fishermen in Çanakkale, Turkey, July, 2017. We examined a total of 40 fish (20 non-infested and 20 infested) assessed biometric indices, haematological parameters serum biochemical variables. The hepatosomatic index gonadosomatic infested chub lower than those fish. Blood haematocrit ratio haemoglobin concentrati...

Plants can be effectively used as bio-monitors of environmental pollution. However, how the particulate matter (PM) and heavy metal retention ability of plants changes in different areas with human disturbance along with monsoon has not yet been investigated in urban ecosystems. In this study, we measured the amount of PM and heavy metals such as Ni, Cr, Cu, Pb, and Zn accumulated by the leaves...

Serotonin (5-HT) is an important neurotransmitter and neuromodulator that controls a variety of sensory and motor functions through 5-HT receptors (5-HTRs). The 5-HT4R subfamily is linked to Gs proteins, which activate adenylyl cyclases (ACs), and is involved in many responses in peripheral organs. In this study, the 5-HT4R from Apostichopus japonicus (Aj5-HT4R) was identified and characterised...

Katherine N. Theken, Yangmei Deng, Robert N. Schuck, Akinyemi Oni-Orisan, Tricia M. Miller, M. Alison Kannon, Samuel M. Poloyac, and Craig R. Lee Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina; and Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pen...

We determine the Chow rings of the complex algebraic groups E6 and E7, giving generators and relations in terms of Schubert classes of the corresponding flag varieties. This is a continuation of the work of R. Marlin on the computation of the Chow rings of SOn, Spinn,G2, and F4.

Most cases of ciguatera poisoning reported in the past have involved Canadians who ate fish in the Caribbean while on holiday. These cases have implicated grouper in the Dominican Republic(1,2), kingfish in Jamaica, and barracuda in Haiti(3). A fish casserole caused the illness in 57 people during a trip to Cuba(4). Ciguatera poisonings have also been reported in Canada as a result of importing...