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GABAergic, somatostatin-containing bitufted interneurons in layer 2/3 of rat neocortex are excited via glutamatergic excitatory postsynaptic potentials (EPSPs) by pyramidal neurons located in the same cortical layer. Pair recordings showed that short bursts of backpropagating dendritic action potentials (APs) reduced the amplitude of unitary EPSPs. EPSP depression was dependent on a rise in den...

Hodgkin's lymphoma (HL) is a lymphoid neoplasm characterized by Hodgkin's and Reed-Sternberg (H/RS) cells, which is regulated by CD99. We previously reported that CD99 downregulation led to the transformation of murine B lymphoma cells (A20) into cells with an H/RS phenotype, while CD99 upregulation induced differentiation of classical Hodgkin's lymphoma (cHL) cells (L428) into terminal B-cells...

Hodgkin-Reed-Sternberg (H-RS) cells are clonal B cells carrying Ig gene rearrangements. However, in situ hybridization methods failed to demonstrate Ig gene expression in H-RS cells of classical Hodgkin's disease (HD). Because somatic mutations rendering potentially functional Ig gene rearrangements nonfunctional were detected in some cases of the disease, it was speculated that H-RS cells in c...

space subcode of a Reed-Solomon (SSRS) code Over GF(2"') is the set of RS codewords, whose components all lie in a particular GF(2)subspace of GF(2"). SSRS codes include both generalized B C H codes and "trace-shortened" Rs codes [2][3] as special casea. In this paper we present an explicit formula for t h e dimension of an arbitrary RS subspace subcode. Using this formula, we And that in many ...

Our argument in brief The annual cost of hepatitis B immunization of all the newborns alone in India would be Rs. 250 crores, whereas the budget for TB control in India this year is only Rs. 105 crores. Given such a high cost, all options to reduce the cost of Hepatitis -B immunization need to be seriously considered in detail. This cost can be reduced to one-fifth if intradermal route is used....

Richter's syndrome (RS), defined as the transformation of chronic lymphocytic leukemia (CLL) into an aggressive lymphoma, is seen in about 2–10% of all CLL patients. The prognosis of RS is extremely poor with a median survival of about 6 months, although patients with clonally unrelated RS may have a better prognosis. No randomized controlled trials exist to date regarding therapeutic strategie...

The Rotating-Stall (RS) through a rotor-cascade of an axial compressor were numerically investigated with an unsteady two-dimensional finite-volume density based computer code. To validate the computer code, a test case was prepared and the good agreement of the compared results has given the adequate assurance of the code. The RS was incepted with a 40% reduction in flow coefficient and a 0.4%...