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AIM OF THE STUDY To assess the impact of international consensus conference guidelines on the attitude of Swiss specialists when facing the decision to treat chronic hepatitis C patients. METHODS Questionnaires focusing on the personal situation and treatment decisions were mailed to 165 patients who were newly diagnosed with hepatitis C virus (HCV) infection and enrolled into the Swiss Hepat...
چکیده نمایشگاه های جهانی یا اکسپو عنوانی ست که از سال 1851 میلادی در لندن توسط همسر ملکه انگلستان شکل گرفت ، هدف اولیه این نمایشگاه ها نمایش دستاورد های صنعتی بود، اما در طول 165 سال که این نمایشگاه های برگزار گردیدند ، رویکرد آنها تغییر کرده است . در هر دوره به یک شعار که در واقع دغدغه اصلی جهان، در آن زمان بوده است ، پاسخ داده شده و راه حل کشور های مختلف در مورد آن موضوع به نمایش گذارده شد...
Growth of new blood vessels (angiogenesis), required for all tumor growth, is stimulated by the expression of vascular endothelial growth factor (VEGF). VEGF is up-regulated in all known solid tumors but also in atherosclerosis, diabetic retinopathy, arthritis, and many other conditions. Conventional VEGF isoforms have been universally described as proangiogenic cytokines. Here, we show that an...
c-c motif chemokine 22 (ccl22) c16a genetic variation (rs4359426) and c-c chemokine receptor type 4 (ccr4) c1014t variation (rs2228428) have been suggested to affect the expression level of the cognate proteins. here we tried to investigate the plausible association of these polymorphisms with development of colorectal cancer. 165 patients with colorectal adenocarcinoma (age 54.4±13.4) and 150 ...
RATIONALE Systemic sclerosis (SSc) is characterized by widespread microangiopathy, fibrosis, and autoimmunity. Despite the lack of angiogenesis, the expression of vascular endothelial growth factor A (VEGF) was shown to be upregulated in SSc skin and circulation; however, previous studies did not distinguish between proangiogenic VEGF(165) and antiangiogenic VEGF(165)b isoforms, which are gener...
This paper describes an ontology model (conceptual model) based on the ITU-T Recommendation G.805 for transport network architectures. The goal is to take a step forward to the autonomic applications for transport network operation and management. Besides the conceptual model description and explanation, including its main elements (classes, properties and constraints), this paper also includes...
BACKGROUND Comparing published trial patients and non-trial patients in clinical practice, clinicians often doubt whether critically ill patients are sufficiently represented in randomised clinical trials. PATIENTS AND METHODS This study evaluated the extent of infection with multidrug-resistant (MDR) pathogens, anti-microbial combination therapy, off-label use and targeted-treatment in trial...
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