BACKGROUND Idiopathic pulmonary fibrosis is a chronic progressive disorder with a poor prognosis. METHODS We conducted a double-blind, randomized, placebo-controlled multicenter study that assessed the effectiveness over one year of a high oral dose of acetylcysteine (600 mg three times daily) added to standard therapy with prednisone plus azathioprine. The primary end points were changes bet...

BACKGROUND In patients with cirrhosis, pharmacologic or endoscopic treatment may control variceal bleeding. However, the effects of early administration of a somatostatin analogue followed by endoscopic treatment are unknown. METHODS We studied the effects of treatment with vapreotide, a somatostatin analogue, begun before endoscopic treatment in 227 patients with cirrhosis who were hospitali...

BACKGROUND Fluid resuscitation may be detrimental when given before bleeding is controlled in patients with trauma. The purpose of this study was to determine the effects of delaying fluid resuscitation until the time of operative intervention in hypotensive patients with penetrating injuries to the torso. METHODS We conducted a prospective trial comparing immediate and delayed fluid resuscit...

This study was motivated by the fact that teachers had many difficulties adopting 2013 curriculum, particularly new curriculum set at a private Madrasah Ibtidaiyyah. The goal of this to determine teachers' grasp Curriculum in terms planning, implementation, and assessment learning process. study's subjects were seven it done start 2021/2022 school year. is qualitative using descriptive method. ...

Nasopharyngeal cancer (NPC) is a type of in Southeast Asia, with 30-80 cases annually per 10,000 population. Based on the data, about 80% patients advanced-stage are diagnosed first, while 20% develop metastases after therapy. Prognostic assessment essential for optimization treatment. Malnutrition one consequences decreased response to treatment, quality life, and survival. The patient's album...

The risk of developing glaucoma increases dramatically with age (see table 1). OAG in people under age 40 is very rare (72), but in the Framingham, Massachusetts study, approximately 0.9 percent of people aged 65-69 and 4.4 percent of people aged 80-84 had the disease (94). Given this trend and the figures discussed above, a reasonable estimate of the total number of people over age 65 with OAG...