BACKGROUND Wilms tumor (WT) is a pediatric tumor of the kidney, the treatment of which includes heavy chemotherapy. Affected children would likely benefit from more targeted therapies with limited side effects. Establishment of relevant orthotopic WT xenografts is important to better understand mechanisms of WT growth and for preclinical drug testing. PROCEDURE Here we established and charact...

Corncob is one of the industrial waste has cellulose content of 39.1 wt%, which makes it has high potential to be a raw material in the production of cellulose nanocrystal. Corncob was delignificated with 3.5 wt% HNO3 and NaNO2 10 mg, precipitated process with 17.5 wt% NaOH, and bleached with 10 wt% H2O2. Cellulose nanocrystal was obtained by hydrolysis using 45 wt% H2SO4. Corncob and cellulose...

acrylamide was grafted in low density polyethylene during melt processing in the presence of a free radical initiator using a torque rheometer in a closed system. effects of processing time, acrylamide and benzoyl peroxide concentrations were studied. ftir studies revealed that the degree of grafting increased by an increase in acrylamide concentration. maximum grafting was obtained at 7 minute...

the methanol extract of ichnocarpus frutescens r.br. root (meif) was evaluated for its anti-pyretic potential on normal body temperature and yeast-induced pyrexia in albino rats. yeast suspension (10 ml/kg body wt.) increased rectal temperature 19 h after subcutaneous injection. the meif, at doses of 100, 200, and 300 mg/kg body wt., p.o., produced significant reduction in normal body temperatu...

different amounts of nanoclay were incorporated into the acrylic resin matrix at 0, 1, 3, and 5 wt.% loadings. the coatings were applied on low carbon steel plates. optical microscopy, sedimentation test, transmission electron microscopy, and x-ray diffraction were employed to investigate the dispersion of nanoclay in matrix. the corrosion resistance of coatings was evaluated by electrochemical...

A polymorphic glucocorticoid receptor (GR(Qn)) with an expanded CAG track and two silent mutations, when compared with the sequence of other isoform (GR(wt)), is found in two outbred mouse lines that were produced by selection for high (SH) or low (SL) stress response from high or low heat loss lines of mice, respectively. The GR(Qn) allele, which is also found in 5 of 16 commonly used inbred m...

Activation of A2A adenosine receptors (A2ARs) protects kidneys from ischemia-reperfusion injury (IRI). A2ARs are expressed on bone marrow-derived (BM-derived) cells and renal smooth muscle, epithelial, and endothelial cells. To measure the contribution of A2ARs on BM-derived cells in suppressing renal IRI, we examined the effects of a selective agonist of A2ARs, ATL146e, in chimeric mice in whi...

Calorimetric data can provide a basis for determining potential hazards in reactions, storage, and transportation of process chemicals. This work provides calorimetric data for the thermal decomposition behavior in air of 50wt.% hydroxylamine/water (HA), both with and without added stabilizers, which was measured in closed cells with an automatic pressure tracking adiabatic calorimeter (APTAC)....