Narendra et al. (see p. 795 of this issue) have made an exciting new discovery that links the fields of mitochondrial quality control and the genetics of Parkinson's disease (PD). Through an elegant series of high-resolution imaging experiments, they are the first to provide evidence that the PARK2 gene product Parkin is selectively recruited to damaged or uncoupled mitochondria. This recruitme...

An ant colony optimization approach for the preference-based shortest path search Seung-Ho Ok, Woo-Jin Seo, Jin-Ho Ahn, Sungho Kang and Byungin Moon* School of Electrical Engineering and Computer Science, Kyungpook National University, 1370 Sankyuk-dong, Buk-gu, Daegu 702-701, Korea; Department of Electronic Engineering, Hoseo University, 165 Sechul-ri, Baebang-myun, Asan, Chungnam 336-795, Kor...

Health screening has been shown to have beneficial effects on health outcomes in adults with intellectual disability. However, the nature of the population, which makes it difficult to recruit, has meant past studies have been relatively small and effect estimates unstable. This study conducted a pooled analysis of two randomised trials and one cohort study, containing a total of 795 participan...

(795 articles) Oncogenes and Tumor Suppressors • (4217 articles) Neoplasia • (149 articles) Genomics • (1086 articles) Gene Expression • (3667 articles) Clinical Trials and Observations • Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in par...

Seok Min Jin and Richard J. Youle* Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Center Drive, 10-5D37 Bethesda, MD USA *Author for correspondence ([email protected]) Journal of Cell Science 125, 795–799 © 2012. Published by The Company of Biologists Ltd doi:10.1242/jcs.093849 This article is part of a...

We demonstrate a miniature microfabricated saturated absorption laser spectrometer. The system consists of miniature optics, a microfabricated Rb vapor cell, heaters, and a photodetector, all contained within a volume of 0.1 cm(3). Saturated absorption spectra were measured with a diode laser at 795 nm. They are comparable to signals obtained with standard table-top setups, although the rubidiu...

We report the generation of a continuous-wave squeezed vacuum resonant on the Rb D1 line (795 nm) using periodically poled KTiOPO4 (PPKTP) crystals. With a frequency doubler and an optical parametric oscillator based on PPKTP crystals, we observed a squeezing level of -2.75+/-0.14 dB and an antisqueezing level of +7.00+/-0.13 dB. This system could be utilized for demonstrating storage and retri...

Intra-abdominal carcinomatosis after prophylactic oophorectomy in ovarian-cancer-prone families. Lancet 1982;2:795–7. (18) Struewing JP, Watson P, Easton DF, Ponder BA, Lynch HT, Tucker MA. Prophylactic oophorectomy in inherited breast/ovarian cancer families. J Natl Cancer Inst Monogr 1995;17:33–5. (19) Kemp GM, Hsiu JG, Andrews MC. Papillary peritoneal carcinomatosis after prophylactic oophor...

This paper reports on an experiment where 795 human participants answered to the questions taken from second language proficiency tests that were translated to their native language. The output of three machine translation systems and two different human translations were used as the test material. We classified the translation errors in the questions according to an error taxonomy and analyzed...

We report on a mother and her two sons who had a direct duplication of chromosome region 8p22-8p23.1 without dysmorphic features and only mild mental retardation. The patients have been studied using G banding, chromosome painting, and FISH using cosmid probes specific for the region 8p23.1-8pter. Comparison of the phenotypes of our patients and ofpublished patients with an inversion duplicatio...