Synaptogenesis requires orchestrated intercellular communication between synaptic partners, with trans-synaptic signals necessarily traversing the extracellular synaptomatrix separating presynaptic and postsynaptic cells. Extracellular matrix metalloproteinases (Mmps) regulated by secreted tissue inhibitors of metalloproteinases (Timps), cleave secreted and membrane-associated targets to sculpt...

Migration of labor in response to structural changes in the U.S. economy is explored. An empirical study of the migration decision and wage determination is used to evaluate: 1) whether unemployment plays a larger role in motivating the decision to migrate than spatial wage differences and 2) whether the population can be characterized as homogeneous regarding migration and wage determination. ...

The purpose of this study was to examine the effect of specific endurance (Yo-Yo Intermittent recovery test level 1, Yo-Yo IR1) on match performance in male youth soccer. Twenty-one young, male soccer players (age 14.1 +/- 0.2 years) were involved in the study. Players were observed during international championship games of corresponding age categories and completed the Yo-Yo IR1 on a separate...

Mailing address: Rua Minas Gerais, 99, ap. 704, Edifício Maria Del Carmem, Centro – 86020-060 – Londrina, PR, Brasil E-mail: [email protected] ABSTRACT Karate practice can promote beneficial adaptations on the health-related components of physical fitness. Among the components, the maximum oxygen uptake ( O2max) is an important indicator of cardiorespiratory fitness, as it is also a stron...

We investigated the effect of gradual-elastic compression stockings (GCSs) on running economy (RE), kinematics, and performance in endurance runners. Sixteen endurance trained athletes (age: 34.73 ± 6.27 years; VO2max: 62.83 ± 9.03 ml·kg(-1)·min(-1); 38 minutes in 10 km; 1 hour 24 minutes in half marathon) performed in random order 4 bouts of 6 minutes at a recent half-marathon pace on a treadm...

INTRODUCTION There is an established link between smoking, abnormal heart rate (HR) values, and impaired cardiovascular health in middle-aged or older populations. The purpose of this study was to examine the effects of smoking on resting HR and on HR responses during and after exercise in young adults. METHODS A sample of 298 young adults (159 men), aged 20-29 years old, were selected from a...

planned pregnancy among these countries is strikingly reflected in the disparity in abortion rates. The overall U. S. abortion rate (25.9 abortions per 1,000 women aged 15–44) is 1.7 times that of Canada (15.3 per 1,000) and more than four times that of the Netherlands (6.0 per 1,000).5 Differences in pregnancy rates, however, are not so marked. Again, the United States reports the highest rate...

The neuromuscular blocking agent cisatracurium is frequently used adjunctively in anesthesia to facilitate endotracheal intubation and to provide muscle relaxation during surgery. We aimed to determine the pharmacokinetics (PK)/pharmacodynamics (PD) of cisatracurium in patients with congenital heart defects (CHDs), such as ventricular septal defects and atrial septal defects, and to assess the ...