The Src family tyrosine kinase Hck possesses two phosphorylation sites, Tyr(527) and Tyr(416), that affect the catalytic activity in opposite ways. When phosphorylated, Tyr(527) and residues C-terminal to it are involved in an inhibitory intramolecular interaction with the SH2 domain. However, this sequence does not conform to the sequence of the high affinity SH2 ligand, pYEEI. We mutated this...

Urinary stone is a worldwide disease and percutaneous nephrolithotomy (PCNL) is the most commonly used operation for staghorn calculi. Research indicated that SFR for staghorn calculi in one stage of PCNL showed 50%-91% results, under standard operation, standard instrument and professional treatment route. The present study aimed to explore the clinical factors of stone free rates (SFR) after ...

BACKGROUND Many factors impact caregivers' cognitive health and, by extension, their ability to provide care. This study examined the relationship between psychosocial factors and cognitive performance among dementia caregivers and established a virtual cohort of caregivers for future research. METHODS Data on 527 caregivers were collected via a Web-based survey that assessed cognitive perfor...

Penelitian ini bertujuan untuk mengetahui struktur komunitas plankton yang meliputi kelimpahan, keanekaragaman, keseragaman, dominansi, kesamaan habitat di Perairan Pantai Tanjung Kasuari. Hasil pengamatan menunjukkan bahwa fitoplankton ditemukan terdiri dari 3 kelas yaitu Bacillariophyceae (27 genera), Cyanophyceae (1 genus), dan Dinophyceae (3 genera): zooplankton 7 kelompok Crustacea (8 Prot...

Abu-Omar and Kittaneh [Numerical radius inequalities for products of Hilbert space operators, J. Operator Theory 72(2) (2014), 521-527], wonder what is the smallest constant c such thatw(AB) ? c||A||w(B) all bounded linear operators A, B on a complex with A positive. Here, w(?) stands numerical radius. In this paper, we prove that = 3?3/4.

Eva Apostolou and Charles Doyen (eds), Obolos 10. Coins in the Peloponnese. La monnaie dans le Péloponnèse. Proceedings of Sixth Scientific Meeting Friends Numismatic Museum, Argos, May 26–29, 2011. Volume 1: Ancient Times. 2: Byzantine Modern BCH Supplément 57. pp. 527 + 285, with figs, ills, maps. Athens: École Française d’Athènes, 2017. ISBN 978-2-86958-279-8, paperback €90.

MORBIDITY AND MORTALITY WEEKLY REPORT Epidemiologic Notes and Reports 525 C h io ro q u in e -R e s is ta n t Plasmodium falciparum M a la ria A c q u ire d in Ea st A fr ic a — P e n n sy lva n ia 527 F o o d -B o rn e Illn e ss d ue to In ad ve rte n t C o n su m p t io n o f M a r iju a n a — C a lifo rn ia 533 M easles, U .S . — W e ek s 3 7 -4 0 , 1981 Current Trends 527 T h e C o s t o f ...

OBJECTIVES We compared characteristics and outcomes of children enrolled in a randomized controlled trial (RCT) comparing oral amoxicillin and benzyl penicillin for the treatment of chest indrawing pneumonia vs. children who received routine care to determine the external validity of the trial results. STUDY DESIGN AND SETTING A retrospective cohort study was conducted among children aged 2-5...

The major site of tyrosine phosphorylation of the transforming protein of Rous sarcoma virus, pp60v-src (tyrosine-416), is different from the major site of tyrosine phosphorylation of its nontransforming normal cellular counterpart, pp60c-src. We have shown that antibodies against a synthetic peptide modeled on the carboxyl-terminal 13 residues of pp60c-src specifically immunoprecipitate the ma...

Background/aim: Mediastinal lymph nodes are the second most commonly affected lymph nodes in tuberculous lymphadenitis. It is often difficult to diagnose tuberculosis in patients with lymphadenopathy without parenchymal lesions. The aim of this study was to describe the diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with isolated m...