A series of glycan-coated quantum dots were prepared to probe the effect of glycan presentation in intracellular localization in HeLa and SV40 epithelial cells. We show that glycan density mostly impacts on cell toxicity, whereas glycan type affects the cell uptake and intracellular localization. Moreover, we show that lactose can act as a "Trojan horse" on bi-functionalized QDs to help intrace...

BACKGROUND Reduced muscle aerobic capacity in COPD patients has been demonstrated in several laboratories by phosphorus magnetic resonance spectroscopy and by analysis of oxygen uptake (VO2) kinetics. COPD patients are usually elderly, hypoxemic, poorly active with muscle atrophy, and often malnourished. Under these conditions there is usually reduction of O2 delivery to the tissues (bulk O2 fl...

There are several typographical errors in this Article. In the legend of Figure 7, ‘‘(Open triangles with dashed line)’’ should read, ‘‘(Open triangles with solid line)’’ and, ‘‘(Open circles with solid line)’’ should read, ‘‘(Open circles with dashed line)’’. In the Results, JAR 41 elicits human complement-mediated bactericidal activity with second anti-fHbp mAbs subsection, ‘‘(for example, JA...

In arid and semi-arid environments, groundwater plays a significant role in the ecosystem. In the last decades, groundwater levels have decreased due to the increasing demand for water, weak irrigation management and soil damage. For the effective management of groundwater, it is important to model and predict fluctuations in groundwater levels. In this study, groundwater table in Kashan plain ...

Background: Placenta previa (P.P) is a condition where the lower edge of placenta lies close to internal os. It may partially or completely cover Objectives: To determine frequency on ultrasonography in females with history Caesarean section. Methodology: This descriptive study was held Ghurki Trust Teaching Hospital Lahore and Tehsil Headquarter Hospital, Pattoki. Convex Probe Esotae 2.5 5-7MH...

Five observations of the hard X-ray spectrum of Her X-1 from RXTE show that the ∼ 41 keV energy of the cyclotron scattering line is constant within statistics of a few percent per observation. The overall spectral shape, on the other hand, varies somewhat, with an RMS of 2%. If the 41 keV feature truly originates as cyclotron resonance scattering in an unchanging 3 × 10 Gauss dipole field not f...

Forty-eight hours after unilateral nephrectomy in young male Sprague-Dawley rats the concentrations of free methionine, alanine and tyrosine in renal cortical tissue were increased by 15-65 percent while the corresponding plasma concentrations decreased by 23-35 percent. The renal cortical concentrations of valine and leucine increased by 41 percent and 26 percent while plasma concentrations re...