Proof. Assume the hypothesis and the falsity of either conclusion. Construct matrix A of 2x + 2 rows and 4x+4 columns, with entries + 1 and — 1. The first column contains exclusively +1, and the second column — 1. Set up one-to-one correspondences between rows of A and elements of D ; between columns other than the first two of A and blocks of D. Enter +1 if the element is contained in the bloc...

BACKGROUND In a placebo-controlled trial of the peptide-based therapeutic HIV-1 p24Gag vaccine candidate Vacc-4x, participants on combination antiretroviral therapy (cART) received six immunizations over 18weeks, followed by analytical treatment interruption (ATI) between weeks 28 and 52. Cell-mediated immune responses were investigated as predictors of Vacc-4x effect (VE) on viral load (VL) an...

In this article, we perform a statistical analysis of reoccurrence of opportunistic diseases for HIV-1 infected patients vaccinated with Vacc-4x and Vacc-5q therapeutic vaccines, comparing to a control group. The Peña-Hollander model for recurrent events is used to compare the vaccinated patients from the clinical studies and a control group of patients on HAART with similar conditions of the i...

BACKGROUND Adenovirus (Ad), associated with significant morbidity, has no topical treatment. A leading CTC compound (CTC-96), a Co(III) chelate, was found to have potent in vitro and in vivo antiviral efficacy against herpes viruses. In this study CTC-96 is being tested for possible anti-Adenovirus activity. METHODS The biological anti-adenovirus activity of CTC-96 in concentrations from 5 to...

Two experiments were performed to examine the ability of human pancreatic growth hormone releasing factor (hGRF) administration to stimulate endogenous growth hormone (GH) secretion in lambs. Each study utilized eight Dorset wether lambs in replicated 4 X 4 Latin square experiments. Growth hormone response (integrated area under the curve for 150 min post-injection) for 0, 1, 5 and 10 microgram...

Postantibiotic effects were induced in Pseudomonas aeruginosa clinical isolates after a short time (1 hr) treatment with 2Xand 4X-MICs of different antimicrobial agents (fluoroquinolones, amikacin, aztreonam, and β-lactam antibiotics). The postantibiotic effect of fluoroquinolones on bacterial regrowth and virulence factor activity were more than that of the amikacin, and the highest postantibi...

INTRODUCTION The number of liver resections significantly increased worldwide in the last 20 years. In many hepatic tumours, liver resection remains the best therapeutic option. A difficult intraoperative goal is to obtain a safe haemostasis on the transection plane. Technological innovation in recent decades allowed the development of different tools that allow better control of bleeding, fast...

DS-CDMA in the modern civil and military communications is widely used. Due to its low power spectral density, the DS-CDMA signal always floods in the background noise, bringing difficulties to the signal’s reconnaissance. Therefore, DS-CDMA signal detection has attracted attention of researchers. In this paper, the fourthorder moment chip ( ( ) τ , 0 , 0 4x m ) of DS-CDMA signals is derived, a...