The effect of tetrahydro-9-aminoacridine (THA) and related compounds on ligand binding to the dissociative anesthetic (phencyclidine, PCP) receptor site was assessed using a rat brain homogenate assay. THA displaced the dissociative anesthetic ligand [3H]N-(1-[2-thienyl]cyclohexyl)3-4-piperidine [( 3H]TCP) binding with an IC50 of 26 microM. Other acridine derivatives displayed similar potency a...

The type of bearing material that should be used in revision surgery after the failure of ceramic-on-ceramic total hip arthroplasty (THA) remains controversial. In the case of ceramic fracture, the residual ceramic particles can cause consequent metallosis when metal implants are used for revision THA. On the other hand, in the case of THA failure without ceramic fracture, revision THA with a m...

This study aims to propose latitude cut deviation for differentiating hip arthroplasty types and evaluate its diagnostic utility in distinguishing total (THA) from hemiarthroplasty using radiography. After assessing various cup designs top manufacturers THA hemiarthroplasty, we conducted a retrospective on 40 patients (20 20 hemiarthroplasty). Three readers independently evaluated the radiograp...

Resonance Raman spectroscopy at ambient temperature and 77 K has been used to probe the structures of the copper sites in Achromobacter cycloclastes nitrite reductase. This enzyme contains three copper ions per protein molecule and has two principal electronic absorption bands with lambda max values of 458 and 585 nm. Comparisons between the resonance Raman spectra of nitrite reductase and blue...

Regulation of Vascular Cell Behavior by Collagen : Form Is Function Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2001 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/01.RES.88.5.458 2001;88:458-459 Circ Res. http://circres.ahajournals.org/content/88/5/458...

Conceptualization of Gastrointestinal Illness 337 Biomedical Model 337 Biopsychosocial Model 338 Early Life 339 Early Learning 339 Culture and Family 340 Psychosocial Environment 340 Life Stress and Abuse 341 Psychological Factors 341 Coping and Social Support 342 Brain-Gut Axis 342 Stress and Gastrointestinal Function 342 Role of Neurotransmitters 343 Regulation of Visceral Pain 343 Effects of...

Fractures of the femoral neck in elderly patients can be treated by internal fixation, hemiarthroplasty, or total hip arthroplasty (THA), and the treatment modality used should be determined on the basis of considerations of the degree of fracture displacement, age, functional demands, and the risk factors for surgery and anesthesia. We studied 85 active elderly patients who underwent minimally...