BACKGROUND Postthrombotic syndrome (PTS) is a frequent, chronic complication of DVT. The effectiveness and safety of available treatments are unknown. The objective of this study was to systematically review the literature to assess whether pharmacologic and compression therapies are effective and safe for the treatment of PTS. METHODS We sought to identify randomized controlled trials (RCTs)...

Atomic absorption spectrometry was used for red cell (MgRC) and plasma Mg (MgPL) measurement (mEq/L) in 24 normal individuals (Nls), aged 42.16 +/- 16 years, and 44 carefully selected consecutive patients (pts), aged 60.68 +/- 10 years with cor pulmonale. The results showed the following: (1) normal MgPL (1.69 +/- 0.19) and MgRC (4.22 +/- 0.32) in Nls; (2) decreased MgpL (1.56 +/- 0.23) and MgR...

OBJECTIVE To ascertain the effect of intravesical instillation of Alpha 2-b Interferon (IFN a-2) 10 million I.U. in 50 ml physiological saline as a monotherapy and in combination with Farmarubicin (FRC) 50 mg dissolved together in 50 ml of physiological saline. These substances were administered four times during the first month after TUR-BT and then once monthly for one year either in the form...

T-DM1 is standard treatment in patients (pts) with HER2-positive breast cancer residual disease after neoadjuvant therapy. The GIM26-TRASTHER study of the Gruppo Italiano Mammella (GIM) group collects data from Italian compassionate use program that anticipated drug reimbursement. Inclusion criteria mirrored Katherine trial. We registered adverse events (AEs) were considered to be certainly/pro...

Abstract Background Brugada syndrome (BS) is a rare inherited channelopathy associated with sudden cardiac death (SCD) and family screening (FS) of index patients (pts) recommended. However, data about pts identified through FS lacking. Aim To compare to non-index systematic FS. Methods Single-center retrospective study BS followed by the Arrhythmology Department. was offered 1st degree relativ...

7505 Background: MCL is a rare lymphoma without standard of care but several regimens have demonstrated clinical activity, the majority based on traditional chemotherapy. We hypothesized that adding venetoclax (V) to R2 would be safe and effective in pts irrespective age, morphology or stage. Here we present safety efficacy data from on-going phase 1b study + V with newly diagnosed MCL. Methods...

Potted grapevines of 140 Ruggeri (Vitis berlandieri × Vitis rupestris), a good Cl(-) excluder, and K 51-40 (Vitis champinii × Vitis riparia 'Gloire'), a poor Cl(-) excluder, and of a family obtained by crossing the two genotypes, were used to examine the inheritance of Cl(-) exclusion. Rooted leaves were then used to further investigate the mechanism for Cl(-) exclusion in 140 Ruggeri. In both ...

BACKGROUND/OBJECTIVES We prospectively measured change in quality of life (QOL) during the 2 years after a diagnosis of deep vein thrombosis (DVT) and evaluated determinants of QOL, including development of the post-thrombotic syndrome (PTS). PATIENTS/METHODS Consecutive patients with acute DVT were recruited from 2001 to 2004 at eight hospitals in Canada. At study visits at baseline, and 1, ...

BACKGROUND Posttraumatic stress (PTS) disorder after injury is a significant yet underaddressed issue in the trauma care setting. Parental anxiety may impact a child's risk of future, persistent PTS symptoms after injury. This study aimed to: (1) identify injury incident and demographic variables related to a positive screen for future, persistent PTS symptoms in children; and (2) examine the r...

OBJECTIVE Develop a method for the evaluation of patients nutritional status through a score that expresses universal nutritional status, as well as investigate if that score would be efficient for the prognostic stratification of advanced heart failure (HF) pts. METHODS The score was reached by the selection of evaluation methods that would quantify nutritional status: ideal body weight perc...