Background: Differentiating oligodendrocyte precursor cells (OPCs) into oligodendrocytes could be improved by inhibiting signaling pathways such as Wnt and Notch. 9-cis-retinoic acid (9-cis-RA) and 1,25-dihydroxyvitamin D3 (1,25[OH]2D3) can ameliorate oligodendrogenesis. We investigated whether they could increase oligodendrogenesis by inhibiting the Wnt and Notch signaling pathways.Methods: Co...

Determining ionizing radiation in a geographic area serves to assess its effects on a population's health. The aim of this study was to evaluate the spatial distribution of the background environmental outdoor gamma dose rates in Chihuahua City. This study also estimated the annual effective dose and the lifetime cancer risks of the population of this city. To determine the outdoor gamma dose r...

the significance of research article (ra) abstract as a key academic genre has recently motivated analysts to focus on this neglected area. considering a summary function for abstracts, most genre researchers have adopted the conventionally proposed introduction- method- results- discussion (or conclusion) (imrd) model for analysis. however, the problems reported, especially for results and dis...

background recently, assessment of the atrial motion and deformation indices obtained via doppler myocardial imaging (dmi) has been proposed as a new method of exploring the atrial function. objective our aim was to assess the right atrial (ra) regional function using myocardial velocities, strain, and strain rate imaging (sri) and compare it with the function of the inter-atrial septum (ias) a...

Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease with many genetic factors predisposing to disease susceptibility. The aim of the present study was to investigate the impact of CD226 rs727088 and rs763361 polymorphisms and susceptibility to RA in a sample of the Iranian population. Methods: This case-control study was carried out on 100 patients with RA and 104 healthy su...