نتایج جستجو برای: 2224 years

تعداد نتایج: 990982  

Journal: :Wiley interdisciplinary reviews. Systems biology and medicine 2016
Simon Mitchell Jesse Vargas Alexander Hoffmann

The nuclear factor kappa B (NFκB) family of transcription factors is a key regulator of immune development, immune responses, inflammation, and cancer. The NFκB signaling system (defined by the interactions between NFκB dimers, IκB regulators, and IKK complexes) is responsive to a number of stimuli, and upon ligand-receptor engagement, distinct cellular outcomes, appropriate to the specific sig...

2002
Slavko Bogdanov

We present interstellar scintillation velocity measurements for four millisecond pulsars obtained from long-term monitoring observations with the Arecibo radio telescope at 430 MHz. We also derive explicit expressions that relate the measured scintillation velocity to the effective transverse velocity responsible for the motion of the diffraction pattern for both binary and solitary pulsars. Fo...

Journal: :The Journal of biological chemistry 1961
D P NIERLICH B MAGASANIK

18. SBARRA, A. J., AND KARNOVSKY, M. L., J. Biol. Chem., 235, 2224 (1960). ELSBACH, I?., J. Exptl. Med., 110, 969 (1959). BECKER, H., MUNDER, G., AND FISCHER, H., 2. Physiol. Chem., 313, 266 (1958). BECK, W. S., J: Biol. Chem., 232, 271 (1958). UMBREIT. W. W.. BURRIS. R. H., AND STAUFFER, J. F., Manometric iechnip&s, Ed. 3, Burgess Publishing co., Mmneapolis, 1957, p. 172. SCHWIND, J. L., Blood...

1999
G.A.J. Riegger

Background—The renin-angiotensin system plays an important part in the pathogenesis of congestive heart failure (CHF). This study evaluated the effect of an angiotensin II type 1 receptor antagonist on exercise tolerance and symptoms of CHF. Methods and Results—In this multicenter, double-blind, parallel-group study, 844 patients with CHF were randomized to 12 weeks’ treatment with placebo (n52...

Journal: :Tropical medicine & international health : TM & IH 2008
Thérèse Delvaux Sophal Soeur Tung Rathavy François Crabbé Anne Buvé

OBJECTIVES To document the pilot experience of provision of safe abortion/post-abortion services implemented in 2002 at the Mother Child Health clinic in Sihanoukville, Cambodia, and to profile clients and assess their uptake of post-abortion contraception. METHODS The initial package of safe abortion/post-abortion clinics (SAPAC) services included counselling on family planning and preventio...

2017
ANACLETO CORREIA ANTÓNIO GONÇALVES M. FILOMENA TEODORO

Information security is concerned with the requirements of availability, integrity, and confidentiality of information’s assets, which are fundamental to the long-term survival of an organization. Information security relies in risk management for security risks identification, evaluation and treatment, according to the ISO 31000. The methodologies supporting information security implementation...

2013
J. A. Tumlin C. M. Galphin B. H. Rovin

BACKGROUND AND OBJECTIVE Adrenocorticotropic hormone (ACTH) is able to reduce proteinuria in nondiabetic glomerulopathies through activation of melanocortin receptors (MCR) expressed in the podocyte. To determine the efficacy of ACTH, we conducted a randomized, open-label pilot trial of ACTH gel in patients with advanced diabetic nephropathy. STUDY DESIGN Twenty-three (23) patients with diabe...

2014
MARTINA ZELEŇÁKOVÁ

This paper deals with the research of monthly precipitation trends in climatic stations in Libya and Slovakia. The non-parametric Mann-Kendall statistic test was applied to detect trends and to assess the significance of the trends in the time series. The evaluation was done for the time period from November to October. Trend analysis of rainfall data series for 1970–2010 did not show any clear...

Journal: :International journal of clinical practice 2001
J Casciano J Doyle R Casciano Z Kopp N Marchant S Bustacchini S Arikian R Kim

The objective of this analysis was to assess the cost-effectiveness of achieving 'tight control' versus 'less tight control' of blood pressure, as defined in the UK Prospective Diabetics Study 38, in type II diabetic patients in the UK and Italy. The effect of including doxazosin in a 'tight control' combination therapy was analysed. Given doxazosin's positive impact on lipid levels in addition...

2018
Jirar Topouchian Carlos Labat Sylvie Gautier Magnus Bäck Apostolos Achimastos Jacques Blacher Marcin Cwynar Alejandro de la Sierra Denes Pall Francesco Fantin Katalin Farkas Luis Garcia-Ortiz Zoya Hakobyan Piotr Jankowski Ana Jelakovic Zhanna Kobalava Alexandra Konradi Yulia Kotovskaya Marina Kotsani Irina Lazareva Alexander Litvin Viktor Milyagin Iveta Mintale Oscar Persson Rafael Ramos Anatoly Rogoza Ligita Ryliskyte Angelo Scuteri Yuriy Sirenko Georges Soulis Nebojsa Tasic Maryna Udovychenko Saule Urazalina Peter Wohlfahrt Parounak Zelveian Athanase Benetos Roland Asmar

OBJECTIVE The aim of the Advanced Approach to Arterial Stiffness study was to compare arterial stiffness measured simultaneously with two different methods in different age groups of middle-aged and older adults with or without metabolic syndrome (MetS). The specific effects of the different MetS components on arterial stiffness were also studied. METHODS This prospective, multicentre, intern...

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