Identifying targets of dysregulated microRNAs (miRNAs) will enhance our understanding of how altered miRNA expression contributes to the malignant phenotype of breast cancer. The expression of miR-205 was reduced in four breast cancer cell lines compared to the normal-like epithelial cell line MCF10A and in tumor and metastatic tissues compared to adjacent benign breast tissue. Two predicted bi...

The treatment of high-risk prostate cancer (HRPCa) is a tremendous challenge for uro-oncologists. The identification of predictive moleculobiological markers allowing risk assessment of lymph node metastasis and systemic progression is essential in establishing effective treatment. In the current study, we investigate the prognostic potential of miR-205 in HRPCa study and validation cohorts, se...

MicroRNA-205 (miR-205) was revealed as a novel diagnostic and prognostic biomarker for lung cancer, but the results in the published papers were inconsistent. This meta-analysis aimed to investigate the diagnostic and prognostic roles of miR-205 in patients with lung cancer. Totally, 16 eligible articles were included, among which 10 articles investigated the diagnostic value of miR-205, 5 arti...

PURPOSE miR-205 is significantly up-regulated in endometrioid adenocarcinoma. In this study, the significant anticancer effect of a miR-205 inhibitor was investigated in both endometrial carcinoma and progesterone-resistant endometrial carcinoma cells. RESULTS Compared with Ishikawa endometrial cancer cells, miR-205 was expressed at higher levels in a progesterone-resistant (PR) sub-cell line...

The occurrence of caecal nematode, Subulura brumpti has become more common in quails being maintained in commercial farms in Tamil Nadu, India. Two trials were carried out to study the biology and pathology of S. brumpti in quails. In the first trial, eight grower quails were divided into two groups (T1 and T2) comprising of four birds each. The birds belonged to the group T1 was infected with ...

BMP and Wnt signaling pathways play a crucial role in organogenesis, including tooth development. Despite extensive studies, the exact functions, as well as if and how these two pathways act coordinately in regulating early tooth development, remain elusive. In this study, we dissected regulatory functions of BMP and Wnt pathways in early tooth development using a transgenic noggin (Nog) overex...

OBJECTIVE To determine whether a topical ophthalmic diclofenac sodium formulation containing a proprietary polymeric drug delivery system (ISV-205), when dosed concomitantly with 1% prednisolone acetate, is effective in blocking the intraocular pressure (IOP) response in humans. DESIGN This was a multicenter, prospective, double-masked, parallel, vehicle-controlled study. We included 136 firs...

Data and Methods The study uses data from the 1991 followup of the National Survey of Adolescent Males (NSAM), a nationally representative survey of never-married, noninstitutionalized males aged 15–19. The original wave of face-to-face interviews conducted in 1988 had a response rate of 74%. In the 1991 wave, face-to-face interviews were conducted with 1,676 respondents aged 17–22, for an 89% ...

in block cipher SMS4 Zhang MeiLing, Liu JingMei, Wang XinMei National Key Lab. of Integrated Service Networks, Xidian University. Xi’an, 710071,China Abstract: SMS4 is a 128-bit block cipher with a 128-bit user key and 32 rounds, which is used in the Chinese National Standard for Wireless LAN WAPI. In this paper, all possible differential patterns are divided into several sections by six design...

The random number generator (RNG) is a critical, if not in fact the most important, component in every cryptographic device. Introducing the symmetric radio channel, represented by estimations of location-specific, reciprocal, and timevariant channel characteristics, as a common RNG is not a trivial task. In recent years, several practice-oriented protocols have been proposed, challenging the u...