Thallium-201 myocardial scintigraphy was performed in patients with congenital heart defects to determine whether, by quantification of right ventricular isotope uptake, one could assess the degree of right ventricular hypertrophy and so predict the level of right ventricular pressure. A total of 24 patients ranging in age from 7 months to 30 years was studied; 18 were studied before corrective...

Various studies have been conducted on the mechanisms of host plant resistance (HPR) of cabbage against the diamondback moth (DBM). Understanding the role of wax-bloom has been a major focus of these studies. Our study distinguishes itself from previous research by focusing specifically on outer leaf angle and leaf hardness. The resistance mechanism of cabbage cultivar “Shinsei” against DBM was...

BACKGROUND Rapid resuscitation with oxygen-carrying fluids is critically important in hemorrhagic shock (HS) combat casualties in remote areas where blood is not available. Hemoglobin-based oxygen carrier-201 (HBOC-201) has been shown to increase survival and reduce immune activation following HS in animal models. Recombinant factor VIIa (rfVIIa), a systemic hemostatic agent, is Food and Drug A...

INTRODUCTION: Heterogeneity of cartilage tumours may confound accurate diagnosis and grading resulting in under and over treatment. Improved preoperative assessment of malignancy and grade would be invaluable for developing a rational plan for treatment. We examined correlations between nuclear tracer avidity and malignancy grade in cartilage tumours. METHODS: Between 1996 and 2000, 92 consecut...

The appearance of the right ventricular myocardium on thallium 201 myocardial perfusion images was evaluated in patients with chronic pulmonary hypertension and compared to patients without pulmonary hypertension. Four groups of patients were studied: 1) eight normals, 2) five patients with angiographically documented coronary artery disease and normal pulmonary artery pressures, 3) ten patient...

Human prostate cancers are dependent on the androgen receptor for their progression. The MUC1 heterodimeric oncoprotein is aberrantly overexpressed in prostate cancers; however, it is not known if MUC1 is of functional importance to these tumors. To assess dependence on MUC1, we synthesized an inhibitor, designated GO-201, which interacts directly with the MUC1-C subunit at its oligomerization ...

Forty endoscopically proven active variceal bleeds were entered in a prospective trial comparing oesophageal tamponade with SMS 201-995 infusion. Oesophageal tamponade controlled 19 of 20 bleeds over the first four hours and 14 of 18 bleeds over 48 hours. SMS 201-995 infusion controlled 18 of 20 bleeds over the first four hours and 10 of 20 bleeds over 48 hours (p = 0.15). No significant differ...

Background Stress cardiac magnetic resonance with adenosine (CMR-A) is a valid test to rule out myocardial ischaemia. We follow-up a cohort of patients with CMR-A due to suspected myocardial ischaemia, considering patients with very high cardiovascular risk. Methods We included all patients with CMR-A between June 2009 and November 2012, considering two groups: those with a very high cardiovasc...

Understanding macromolecular function often relies on the comparison of different structural models of a molecule. In such a comparative analysis, the identification of the part of the molecule that is conformationally invariant with respect to a set of conformers is a critical step, as the corresponding subset of atoms constitutes the reference for subsequent analysis for example by least-squa...

Myocardial imaging using thallium-201 was performed in patients with Kawasaki disease. In two patients whose ECGs showed ischemic changes, the scintiscan demonstrated an area with diminished radioactivity at the site corresponding to electrocardiographic localization of the infarction. Thallium-201 myocardial imaging is useful in the diagnosis of myocardial infarction not only in adults but als...