The present study examined the sensitivity of carnitine palmitoyltransferase I (CPT I) activity to its inhibitor malonyl-CoA (M-CoA), and simulated metabolic conditions of rest and exercise, in aerobically trained and untrained humans. Maximal CPT I activity was measured in mitochondria isolated from resting human skeletal muscle. Mean CPT I activity was 492.8 +/- 72.8 and 260.8 +/- 33.6 microm...

Pilegaard, Henriette, Kristian Domino, Thomas Noland, Carsten Juel, Ylva Hellsten, Andrew P. Halestrap, and Jens Bangsbo. Effect of high-intensity exercise training on lactate/H1 transport capacity in human skeletal muscle. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E255– E261, 1999.—The present study examined the effect of highintensity exercise training on muscle sarcolemmal lactate/H1 tran...

INTRODUCTION Few children in the United States achieve the recommended 60 minutes of physical activity per day. Identifying successful interventions that increase physical activity for children is critical. This observational study evaluated the effects of Move-To-Improve (MTI), a classroom-based physical education program designed for kindergarten to third-grade teachers in New York City publi...

Several studies have shown that extensive training with synthetic speech sounds can result in substantial improvements in listeners' perception of intraphonemic differences. The purpose of the present study was to investigate the effects of listening experience on the perception of intraphonemic differences in the absence of specific training with the synthetic speech sounds being tested. Phone...

Pilegaard, Henriette, Kristian Domino, Thomas Noland, Carsten Juel, Ylva Hellsten, Andrew P. Halestrap, and Jens Bangsbo. Effect of high-intensity exercise training on lactate/H1 transport capacity in human skeletal muscle. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E255– E261, 1999.—The present study examined the effect of highintensity exercise training on muscle sarcolemmal lactate/H1 tran...

Systemic hypoxia produces microvascular inflammation in several tissues, including skeletal muscle. Exercise training (ET) has been shown to reduce the inflammatory component of several diseases. Alternatively, ET could influence hypoxia-induced inflammation by improving tissue oxygenation or increasing mechanical antiadhesive forces at the leukocyte-endothelial interface. The effect of 5 wk of...

This study investigated the influence of cueing on the performance of untrained and trained complex motor responses. Healthy adults responded to a visual target by performing four sequential movements (complex response) or a single movement (simple response) of their middle finger. A visual cue preceded the target by an interval of 300, 1000, or 2000 ms. In Experiment 1, the complex and simple ...

DOHM, G. LYNIS, RICHARD L. HUSTON, E. WAYNE ASKEW, AND PHILIP c. WIZISER. Effects of exercise on activity of heart and muscle mitochondria. Am. J. Physiol. 223(4) : 783-787. 1972.-After 12 weeks on a rigorous schedule of treadmill running, trained and untrained rats were physically exhausted to assess the effects of acute exercise on the activity of several mitochondrial enzyme systems. Skeleta...

SEVERALLS Hospital has 1,825 beds, and fairly recently was divided into a geriatric unit, and five units consisting of two wards and two villas each, with a total of some 750 beds. In spite of repeated advertisements for trained psychiatric social workers over several years, no applications had been received. At the end of 1960 the hospital authorities decided to appoint untrained social worker...

The effect of physical conditioning on skeletal muscle of individuals with spinal cord injuries (SCI) has been investigated. The anterior portion of the deltoid muscle (active in wheel-chair propulsion) of untrained and endurance-trained paraplegics and tetraplegics, as well as that of untrained able-bodied subjects, was studied. The characterization involved fibre type distribution, capillariz...