DXG ([2R-cis]-2-amino-1,9-dihydro-9-[2-[hydroxymethyl]-1,3-dioxolan-4-yl]-6H-purin-6-one) and its prodrug DAPD ([2R-cis]-4-[2,6-diamino-9H-purin-9-yl]-1,3-dioxolane-2-methanol; amdoxovir) are novel 2',3'-dideoxynucleosides (ddNs) displaying activity against human immunodeficiency virus type 1 (HIV-1). In this paper, we describe the development of an enzymatic assay for determining the intracell...

In this work we reported about the use of an electrolyte for lithium-ion batteries (LIBs) based on mixtures 1,3-dioxolane (DOL) and 1,2,2-tetraethoxyethane (TEG). We showed that 1 M LIFSI in TEG : DOL (2 3) displays good transport properties high thermal stability. Graphite lithium-iron phosphate (LFP) electrodes used combination with display capacity, efficiency, high-capacity retention at hig...

In the chiral title compound, C(15)H(22)N(4)O(2)S(2), there are two mol-ecules in the asymmetric unit with distinctly different conformations, as quanti-fied by torsion angles. The dihedral angles between the thio-imidazole rings are 81.59 (5) and 67.04 (4)°. One mol-ecule exhibits local twofold rotation symmetry, while the other displays no local symmetry. Inter-molecular C-H⋯O and C-H⋯S inter...

Pipoxolan HCl (5,5-diphenyl-2-(2'-piperidino-ethyl)-1,3-dioxolane-4-one hydrochloride) is a compound containing a dioxolan moiety that was reported to induce apoptosis in cancer cells. In this study, we investigated the anti-leukemia effects of pipoxolan on U937 leukemia cells both in vivo and in vitro. Cell viability, reactive oxygen species (ROS) production, mitochondrial membrane potential, ...

The chemical valorization/repurposing of biomass-derived chemicals contributes to a biobased economy. Furfural (Fur) is recognized platform produced from renewable lignocellulosic biomass, and furfuryl alcohol (FA) its most important application. aromatic aldehydes Fur benzaldehyde (Bza) are commonly found in the slate compounds via biomass pyrolysis. On other hand, glycerol (Gly) by-product in...