BACKGROUND AND OBJECTIVES The objective of this study was to determine whether long-term exercise training will improve age-related cardiac metabolic derangement using proton magnetic resonance (MR) spectroscopy. MATERIALS AND METHODS Young and old male Fischer 344 rats were assigned to sedentary controls groups {young control (YC) group-3 months of age: YC, n=10; old control (OC) group-22 mo...

The anti-tumour x anti-T-cell bispecific monoclonal antibody (biMAb) OC/TR is a biologically produced biMAb combining the anti-ovarian carcinoma activity of the MOv18 MAb with anti-CD3/T-cell receptor (TCR) complex activity. In this study, the in vitro binding characteristics of the OC/TR biMAb and its tumour targeting potential in nude mice with Hela tumours was studied. Scatchard analysis rev...

BACKGROUND AND OBJECTIVE Reformulated OxyContin(®) (oxycodone-HCl controlled release) tablets (ORF) became available in the United States in August 2010. The original formulation of OxyContin(®) (oxycodone-HCl controlled release) tablets (OC) used a delivery system that did not provide inherent resistance to crushing and dissolving. The objective of this study was to compare the pharmacokinetic...

A composite drag control (CDC) combining the opposition (OC) and spanwise opposed wall-jet forcing (SOJF) methods is investigated. maximum reduction of about 33% obtained for CDC -- much higher than that produced by either individual method (namely, 19% SOJF 23% OC). Flow analysis shows can take advantage both OC to better suppress producing near-wall turbulent structures --vortices streaks. Ou...

 Knowledge of the Saxaul dimensions used in sand dunes stabilization is considered essential for designing live windbreak in desert regions. This research aimed to collect and analysis data and was performed on the pruned and control shrubs of Haloxylon aphyllum L. in Yazd province, Iran in the last two decades. Our review clearly showed the superiority of shrubs pruned at the height of 35 cm i...

to investigate effects of temperature and salinity different levels on germination parameters of german chamomile (matricaria chamomilla), an experiment carried out in complete randomized design as factorial with three replication in department of agronomy, college of agriculture on the university of guilan, in 2014. treatments were including temperature levels (5, 10, 15, 20, 25, 30 and 35 oc)...

Introduction Oleoresin capsicum (OC) or pepper spray, and tear gas (CS) are used by police and the military and produce severe discomfort. Some have proposed that washing with baby shampoo helps reduce this discomfort. Methods We conducted a prospective, randomized, controlled study to determine if baby shampoo is effective in reducing the severity and duration of these effects. Study subject...

Eating an unbalanced diet during pregnancy may induce long-term health consequences in offspring, in particular obesity, insulin resistance, and hypertension. We tested the hypothesis that a maternal diet rich in simple sugars predispose mouse offspring to obesity, glucose intolerance, and cardiovascular diseases in adulthood. Female C57BL/6J mice were fed either a standard chow or a sucrose-ri...