نتایج جستجو برای: 145
تعداد نتایج: 15879 فیلتر نتایج به سال:
BACKGROUND Metastasis is a leading cause of mortality for osteosarcoma (OS) patients, and its molecular pathological mechanisms remain to be elucidated. Previous studies have suggested a significant role of microRNAs (miRNAs) in the control of cancel cell migration and invasion. METHODS Real-time PCR was used to screen the differentially expressed miRNAs between OS with or without metastasis,...
We previously reported that the level of microRNA (miR)-145 is attenuated in human bladder cancer cells. In this current study, we investigated whether intravesical administration of miR-145 could be a potential therapeutic strategy for controlling bladder cancer by using an orthotopic human bladder cancer xenograft model. Following transfection of 253J B-V cells with miR-145, the effects of th...
Phosphoinositide 3-kinases γ and δ (PI3Kγ and PI3Kδ) are expressed in rheumatoid arthritis (RA) synovium and regulate innate and adaptive immune responses. We determined the effect of a potent PI3Kδ,γ inhibitor, IPI-145, in two preclinical models of RA. IPI-145 was administered orally in rat adjuvant-induced arthritis (AA) and intraperitoneally in mouse collagen-induced arthritis (CIA). Efficac...
OBJECTIVE The goal of the present retrospective study is to describe the distribution of the supernumerary teeth in a population of patients that have been attended at the Public Clinic of the Department of Oral Surgery. BACKGROUND Supernumerary teeth and multiple hyperdontia are usually associated with different syndromes, such as Gardner syndrome, or with facial fissures; however, they can ...
Lymphocytic hypophysitis (LH) is a new clinico pathological entity, first described in 1962 by Goudie [46]. With recent advances in radiological investigation and technical refinements of trans-sphenoidal surgery, LH cases are being reported with increasing frequency. A total of 145 cases have been reported to date, 102 of them since 1990, with 121 histologically proven. LH is an autoimmune end...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید