BACKGROUND Ageing adults are likely to expect informal caregiving assistance from a friend or family member, reflecting the reality that most long-term care (LTC) is provided by family and friends. The purpose of the study was to determine the likelihood that expectations of care will be unmet at the onset of functional disability, and the factors that impact that likelihood. METHODS Communit...

Guo, Danping. M.S., Purdue University, May 2015. Kernel and Bulk Density Changes due to Moisture Content, Mechanical Damage, and Insect Damage. Major Professor: Klein Ileleji. Corn (Zea Mays), is one of the major grain crops in the world and moisture content, mechanical damage and insect damage are three factors that affect its quality. The primary goal of this thesis was to investigate the eff...

The hepatitis C virus (HCV) is a positive-strand RNA virus belonging to the Flaviviridae. Its genome carries at either end highly conserved nontranslated regions (NTRs) containing cis-acting RNA elements that are crucial for replication. In this study, we identified a novel RNA element within the NS5B coding sequence that is indispensable for replication. By using secondary structure prediction...

This paper describes the purpose and methods of a single-blinded, clustered and randomised trial of the health impacts of insulating existing houses. The key research question was whether this intervention increased the indoor temperature and lowered the relative humidity, energy consumption and mould growth in the houses, as well as improved the health and well-being of the occupants and there...

Osteogenesis imperfecta (OI) is a genetic disorder causing defects in the development of collagen type I. Clinical signs of affected dachshunds include multiple fractures of bones, joint hyperlaxity and dentinogenesis imperfecta. Recently, a recessive mutation in the SERPINH1 gene was detected in dachshunds and enabled the development of a DNA test to identify dachshunds carrying the mutation. ...

We established the mutant mouse line, B6;CB-SktGtAyu8021IMEG (SktGt), through gene-trap mutagenesis in embryonic stem cells. The novel gene identified, called Sickle tail (Skt), is composed of 19 exons and encodes a protein of 1352 amino acids. Expression of a reporter gene was detected in the notochord during embryogenesis and in the nucleus pulposus of mice. Compression of some of the nuclei ...

Outbreaks of Acanthaster planci, the Crown-of-Thorns starfish, have been known to cause considerable amounts of damage to coral reef systems. Surveys of A. planci populations in Moorea, French Polynesia in 2004 indicated the island was experiencing the beginning stages of an outbreak. The goal of the present study was to survey the population densities of these sea stars at 3 sites on the north...

Using data from Wave 1 (2004-2006) of the National Survey of Fertility Barriers (NSFB), a national probability sample of women ages 25-45, we examine online information-seeking among ever-infertile women. Of the 1352 women who met criteria for infertility, 459 (34%) neither talked to a doctor nor went online for information, 9% went online only for information, 32% talked to a doctor but did no...

[PDF] [Full Text] [Abstract] , March 28, 2007; 27 (13): 3548-3559. J. Neurosci. W. J. Kargo, B. Szatmary and D. A. Nitz Action-Reward Contingencies Adaptation of Prefrontal Cortical Firing Patterns and Their Fidelity to Changes in [PDF] [Full Text] [Abstract] , November 7, 2007; 27 (45): 12176-12189. J. Neurosci. A. Johnson and A. D. Redish Point Neural Ensembles in CA3 Transiently Encode P...

Renal transplantation is well established as the optimal form of renal replacement therapy but is restricted by the limited pool of organs available for transplantation. The whole organ decellularisation approach is leading the way for a regenerative medicine solution towards bioengineered organ replacements. However, systematic preoptimization of both decellularization and recellularization pa...