نتایج جستجو برای: 126
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To investigate miRNA function in human acute myeloid leukemia (AML) stem cells (LSC), we generated a prognostic LSC-associated miRNA signature derived from functionally validated subpopulations of AML samples. For one signature miRNA, miR-126, high bioactivity aggregated all in vivo patient sample LSC activity into a single sorted population, tightly coupling miR-126 expression to LSC function....
Ceramic passive samplers or toximeters (packed with active carbon 1%, w/w, on celite), in combination with the CALUX bioassay have been used as a time-integrated monitoring technique for dissolved dioxin-like PCBs in urban and industrial wastewaters. The technique showed to be reliable during laboratory experiments: (1) PCB-126 amounts extracted from the passive samplers increased linearly with...

 Introduction: The objective of this study was to determine the etiology acute undifferentiated fevers (AUF) in hospitalised children with a tertiary care centre North India. various causes included dengue, malaria, scrub typhus, enteric fever, leptospirosis and Chikungunya. clinical spectrum therapeutic outcome these cases also studied.
 Methods: This retrospective conducted over pe...
Rosa Gini ([email protected]) Paolo Francesconi ([email protected]) Giampiero Mazzaglia ([email protected]) Iacopo Cricelli ([email protected]) Alessandro Pasqua ([email protected]) Pietro Gallina ([email protected]) Salvatore Brugaletta ([email protected]) Daniele Donato ([email protected]) Andr...
BACKGROUND Consistent use of condom provides protection from transmission of human immunodeficiency virus (HIV) infection in couples with sero-discordant HIV status. It also protects against acquiring other strains in HIV positive concordant couples. AIM This study evaluated the use of barrier method of contraception among HIV patients. SUBJECTS AND METHODS This was a descriptive cross-sect...
MicroRNAs are small non-coding RNAs that negatively regulate posttranscriptional gene expression. Several microRNAs have been described to regulate the process of angiogenesis. Previously, we have shown that bone morphogenetic protein 4 (BMP4) increased the pro-angiogenic activity of endothelial cells. In this project, we now investigated how the pro-angiogenic BMP4 effect is mediated by microR...
Rheumatoid arthritis is frequently complicated with respiratory failure, thus threatening patients’ lives. Hypo-methylation of T cells plays a critical role in multiple diseases. DNMT1 is important for gene methylation and is the target gene of microRNA (miR)-126, which thus might regulate T cell gene methylation. This study, therefore, examined the expression of miR-126 during DNG hypo-methyla...
PURPOSE MicroRNAs (miRNA) are involved in and are controlled by epigenetic regulation, and thereby form a reciprocal regulatory circuit. Using next-generation sequencing (NGS)-based miRNA profiling, this study aimed to discover esophageal squamous cell carcinoma (ESCC)-specific miRNAs and miRNA-related epigenetic modulations. EXPERIMENTAL DESIGN NGS-based miRNA profiles were generated for fou...
Mifeng Ren 1, Ting Cheng 1, Junghui Chen 2,*, Xinying Xu 1 and Lan Cheng 1 1 College of Information Engineering, Taiyuan University of Technology, Taiyuan 030024, China; [email protected] (M.R.); [email protected] (T.C.); [email protected] (X.X.); [email protected] (L.C.) 2 Department of Chemical Engineering, Chung-Yuan Christian University, Chung-Li, Taoyuan 32023, Taiwan, Republic o...
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