Melanoma originates from the malignant transformation of epidermal melanocytes, and accounts for most lethal type skin cancer. The dysregulation lipid metabolism is greatly implicated in melanoma pathogenesis. In particular, induction peroxidation-dependent cell death ferroptosis mediates effect immunotherapy. Moreover, aberrant tumor regulates immunotherapy by affecting antigen presentation. H...

Salmonella typhi and paratyphi causes typhoid paratyphoid fevers respectively. Out of the one thousand two hundred six (1206) sample analyzed for Typhoid Paratyphoid using tile method; 748 (62.0%) were positive while 458 (38%) negative. Females found to have highest positivity rate 413 (68.4%), males had 335 (55.5%) rate. The age bracket with 0-10years above (28.3%), followed by 11-20years (26....

This study presents reflectance spectra, determined with an ASD Inc. TerraSpec® spectrometer, of five types of ore and gangue minerals from the Mboukoumassi sylvite deposit, Democratic Republic of the Congo. The spectral absorption features, with peaks at 999, 1077, 1206, 1237, 1524, and 1765 nm, of the ore mineral carnallite were found to be different from those of gangue minerals. Spectral co...

Anaylobacter aguaticus strain KNK607M, which had high NAD-dependent formate dehydrogenase (FDH) activity, was newly isolated. The enzyme, purified to homogeneity, was a dimer composed of identical subunits with a molecular mass of 44 kDa. The specific activity was 9.5 ulmg, and the enzyme was optimum at pH 6.3 and 500C, most stabte at pH 7.0, and stable at 50"C or lovver. The apparent K. yalues...