The title compound, C12H9BrN2OS2, was obtained by reacting 6-bromo-benzo[d]thia-zole-2-carbo-nitrile in iso-propanol with ethyl 2-mercapto-2-methyl-propano-ate at reflux temperature for several hours. The resulting di-methyl-oxyluciferin derivative shows partial double-bond character of the carbon-carbon bond between the two heterocyclic moieties [C-C = 1.461 (3) Å]. This double bond restricts ...

The high dislocation density (ρd) in Fe-C and/or Fe-N martensite is known to be one of the main causes its overall yield strength. Experiments indicate that and, therefore, strength low and medium C steels, follows a well defined behavior with respect background concentration (co). In present work, we introduce model based on finding after γ→α′ sufficiently accommodate/trap most available inter...

Transcriptomics was performed to gain insight into mechanisms of food additives butylated hydroxytoluene (BHT), curcumin (CC), propyl gallate (PG), and thiabendazole (TB), additives for which interactions in the liver can not be excluded. Additives were administered in diets for 28 days to Sprague-Dawley rats and cDNA microarray experiments were performed on hepatic RNA. BHT induced changes in ...

We report a new role for H-NS in Shigella spp.: suppression of repair of DNA damage after UV irradiation. H-NS-mediated suppression of virulence gene expression is thermoregulated in Shigella, being functional at 30 degrees C and nonfunctional at 37 to 40 degrees C. We find that H-NS-mediated suppression of DNA repair after UV irradiation is also thermoregulated. Thus, Shigella flexneri M90T, i...

Of the recently described members of the protein kinase C (PKC) family (-6, -6, -c), no detailed properties of the purified enzymes have been presented. Here we describe the expression of PKC-c in insect cells using a baculovirus vector. The recombinant enzyme has been purified to homogeneity by sequential chromatography on DEAE-cellulose, serine-Sepharose, Mono Q, and Superose 12; the protein ...

In the title complex, [Cu(C(12)H(13)NO(5))(C(12)H(8)N(2))]·0.5H(2)O, the Cu(II) ion is five-coordinated by one N atom and two O atoms from a tridentate Schiff base ligand, derived from the condensation of l-threonine and o-vanillin, and two N atoms from a 1,10-phenanthroline ligand in a distorted square-pyramidal geometry. In the crystal, inter-molecular O-H⋯O hydrogen bonds form a one-dimensio...

Macula densa cells are located within the thick ascending limb and have their basolateral membrane in contact with its own glomerular mesangial cells, which, in turn, are direct contact with smooth muscle cells of afferent arteriole. Macula densa and mesangial cells are involved in an intrinsing renal mechanism that stabilises glomerular filtration rate at the single nephron level, termed tubul...

We highlight fast Li-ion diffusion in hypothetical tetragonal ${\mathrm{Li}}_{10}{\mathrm{GeP}}_{2}{\mathrm{O}}_{12}$ (LGPO), as a counterpart to the well-known phases of orthorhombic (LISICON) LGPO, thio-LISICON, and ${\mathrm{Li}}_{10}{\mathrm{GeP}}_{2}{\mathrm{S}}_{12}$ (LGPS). use extended Car-Parrinello molecular dynamics canonical isobaric-isothermal ensembles, finding first that LGPO is ...