Alternative splicing and trans-splicing events have not been systematically studied in the silkworm Bombyx mori. Here, the silkworm transcriptome was analyzed by RNA-seq. We identified 320 novel genes, modified 1140 gene models, and found thousands of alternative splicing and 58 trans-splicing events. Studies of three SR proteins show that both their alternative splicing patterns and mRNA produ...

BACKGROUND/AIMS Unoperated cataract is the main challenge to blindness reduction in China. This demonstration project in Guangdong Province was designed to test various strategies to improve the cataract surgical rate. METHODS Two strategies (reduction of the cataract surgical fee and training of country doctors in the detection of cataract blindness) were implemented in each of two counties....

prevention of extreme neonatal hyperbilirubinemia in a mature health maintenance organization. Arch Pediatr Adolesc Med. 2000;154:1140-7. 11. Manning DJ, Maxwell MJ, Todd PJ, Platt MJ. Prospective surveillance study of severe hyperbilirubinaemia in the newborn in the United Kingdom and Ireland. Arch Dis Child Fetal Neonatal Ed. 2006; [Epub ahead of print]. http://fn.bmj.com/cgi/rapidpdf/adc.200...

Effects of young stellar clusters on their gas and dust environment are probed using mid-infrared (MIR) wavelengths. The strong MIR [NeIII]/[NeII] ratios (∼ 5 to 10) reveal the presence of current massive stars less than 5Myr. Using MIR line ratios along with optical and NIR data from the literature, composite SEDs are constructed for NGC 1569, NGC 1140 and II Zw40. The stellar SEDs are then us...

We examined intra-specific phylogenetic relationships in leatherside chub, Gila copei. The complete mitochondrial (mt) cytochrome b gene (1140 bp) was sequenced for 30 individuals from 10 populations that span the geographical distribution of this species. Traditional phylogenetic analyses revealed two deeply divergent and evolutionarily distinct mtDNA clades that are geographically separated i...

At least three types of opioid receptors have been identified in the nervous system. In this paper we report molecular cloning and expression of a rat K opioid receptor. PCR was performed on double-stranded cDNA derived from poly(A)+ RNA of the rat striatum with primers similar to those of Libert and co-workers [Libert, Parmentier, Lefort, Dinsart, Van Sande, Maenhaut, Simons, Dumont and Vassar...

OBJECTIVES The objectives were to assess (a) the comparative merits of commonly used disease modifying drugs in the treatment of rheumatoid arthritis (RA) and (b) the influence of age, gender, and disease duration on the outcome of treatment. METHODS Collected analysis (meta-analysis) was performed on results obtained during the first year of treatment in 1140 patients with RA treated with go...

It has been proposed that the acute desensitization of epidermal growth factor receptor (EGF-R) function can be accounted for, in part, by the effect of EGF to increase phosphorylation of the receptor at Ser1046/7 (Countaway, J.L., Nairn, A.C., and Davis, R.J. (1992) J. Biol. Chem. 267, 1129-1140). Here, we show that the mutational removal of this phosphorylation site causes an activation of EG...

Abstract Biochar materials are good examples of sustainable adsorbents with appreciable recent interests and applications in water treatment. The disadvantage using unmodified pristine biochars treatment is mainly related to the inhomogeneous distribution various surface functional groups. Therefore, current study designed functionalize homogenize a selected nanobiochar cation exchanger hydroth...