March 23, 2017 Type Package Title Empirical Bayesian approach to mutational signature discovery Version 1.0.1 Author Rafael Rosales, Rodrigo Drummond, Renan Valieris, Israel Tojal da Silva Maintainer Renan Valieris Description The signeR package provides an empirical Bayesian approach to mutational signature discovery. It is designed to analyze single nucl...

3 Design rationale 4 3.1 Template compilation model . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5 3.2 Specific language features in the design space . . . . . . . . . . . . . . . . . . . . . . . . . . . 6 3.2.1 Named conformance vs. structural conformance . . . . . . . . . . . . . . . . . . . . . . 6 3.2.2 New templates vs. new template parameters . . . . . . . . ....

Several studies investigated the potential role of imaging modalities in prostate cancer patients in case of biochemical recurrence. However, the role of molecular imaging has not been well established yet. Considering the results of the literature and of our own experience, we tried to summarize the potential applications of (11)C-choline PET/CT in prostate cancer patients in case of biochemic...

the study area locates between an active fault system of north anatolian in turkey and active alborz and zagros mountain ranges in iran. the total shortening concluded from arabia-eurasia collision with a rate of 22 mm/year across the ne persia is partitioned  into  two  fault  systems,  right-lateral  strike slip  movements  in  the  turkish-iranian  plateau  like  north tabriz fault system an...

A study’ which involved the administration of relatively large amounts of synthetic 11-dehydrocorticosterone (Ia) and its acetate2 (Ib) to a woman (Case 1) and to a man (Case 2) with Addison’s disease afforded an opportunity to determine what urinary products might be related to this hormone, Thus far it has not been possible to isolate from the urine, in cases of hyperfunctioning lesions of th...

Early localization of biochemical recurrence in patients after radical treatment of prostate cancer is a widely accepted clinical indication of (11)C-choline PET/CT. Its widespread clinical use has prompted the depiction of incidentalomas, unusual sites of metastatic lesions, as well as false positive and negative cases. Over the last 6 years, a total of 454 (11)C-choline PET/CT studies have be...

BACKGROUND Vitamin D (VD) deficiency results in a worse prognosis in patients with chronic lymphocytic leukemia (CLL) and may affect the production of cytokines. Nonetheless, there is the lack of studies dealing with VD supplementation and its impact on chemokines in CLL patients. AIM The primary endpoint of our interventional study was to evaluate the effect of cholecalciferol supplementatio...