At the Research and Production Center of Transfusion platelet production have mainly supported (about 99%) by apheresis. However, apheresis donations have limitations caused by donor fitness due to both their preferences and their platelet pre-count validity. So, it is important to maintain of single donor high-dose plateletpheresis by improving its efficacy and safety. The aim of study was to ...

Eighty per cent of rat blastocysts (Wistar, SW72) cultured for 96 h in NCTC-109 supplemented with fetal calf serum (FCS) hatched from the zona pellucida and developed a trophoblast giant cell lyer. Thirty seven per cent from the rat blastocysts developed an inner cell mass (ICM) which, in about 7% consisted of two germ layers (ectoderm and endoderm) compared to 84% in NMRI mice. A significantly...

our report.' We agree that opportunistic infection was not ruled out and that the recovery after treatment with co-trimoxazole increases the likelihood of pneumocystis pneumonia. No sputum was obtained at any stage in the course of our patient's illness and bronchoalveolar lavage was not performed. We note with interest the frequency with which leucopenia and perhaps lymphopenia has been presen...

Methotrexate toxicity following intravenous (IV) methotrexate is well reported, but there less information on accidental daily dosing of a prescribed weekly dose oral methotrexate. A 70 year old female presented accidentally taking 20 mg for five days, with multiple ulcers, thrombocytopenia (platelets 80 x 109/L [reference range[RR]:150-400 109/L]) and an alanine aminotransferase 820 U/L [RR:10...