BACKGROUND Results of high-dose chemo-radiotherapy (CRT), using the treatment schedules of EORTC study 08972/22973 or radiotherapy (RT) alone were analyzed among all patients (pts) with Non Small Cell Lung Cancer (NSCLC) treated with curative intent in our department from 1995-2004. MATERIAL Included are 131 pts with medically inoperable or with irresectable NSCLC (TNM stage I:15 pts, IIB:15 ...

BACKGROUND To report our early experience with carbon ion irradiation in the treatment of gross residual or unresectable malignant peripheral nerve sheath tumors (MPNST). METHODS We retrospectively analysed 11 patients (pts) with MPNST, who have been treated with carbon ion irradiation (C12) at our institution between 2010 and 2013. All pts had measurable gross disease at the initiation of ra...

Aim: To evaluate the histological changes and immune response of conjuctiva in patients (pts) with lo S.S. Materials and Methods: We studied conjunctiial biopsies from 15 pts with I0 S.S. and 2 normal controls using 1) paraflfn section screening for the quality of conjunctival epithelium (CE), the number of goblet cells (GC) and the degree of inflammation, 2) Mo-abs and Pabs to: Tlymphocytes, T...

BACKGROUND The use of progressive tension sutures has been shown to be comparable to the use of abdominal drains in abdominoplasty. However, the use of barbed progressive tension sutures (B-PTSs) in deep inferior epigastric artery perforator (DIEP) flap donor-site closure has not been investigated. METHODS A retrospective chart review was performed on patients with DIEP flap reconstruction in...

Background: Disease Activity Index for Psoriatic Arthritis (DAPSA) or the minimal disease activity (MDA) are considered defining remission (REM) low (LDA) in secukinumab (SEC) treated patients (pts) with PsA (Psoriatic Arthritis). 1 Currently, limited SEC data available on pts achieving sustained REM clinical trials real-world evidence, using these stringent criteria. Objectives: To report an e...

Radiofrequency ablation (RFA) for atrial fibrillation (AF) can be associated with up to 10% incidence of post-operative pericarditis, suspected more prevalent the advent high-power short duration (HPSD) ablation. This has led widespread use colchicine, an anti-inflammatory medication, prevention post-AF pericarditis. However, utility preventative colchicine remains unproven. To evaluate efficac...

Growth Hormone (GH) and Insulin-like Growth Factor (IGF-1) stimulate proliferation, differentiation and extracellular matrix production in osteoblastic cells. GH and IGF-1 also stimulate recruitment and bone resorption activity in osteoclastic cells. A chronic systemic GH and IGF-1 excess produces an increased bone turn over in acromegalic patients (pts). Osteoporosis, joint alterations and bon...

2535 Background: MBP-426 is a novel liposome encapsulated oxaliplatin (L-OHP) formulation bound to human transferrin, developed to improve the safety and efficacy of L -OHP through the prolongation of circulation time and by targeting transferrin receptors on tumor cells. In vitro, MBP-426 is effective against various human cancer cell lines. This study assessed the toxicity and safety of intra...

The high peak-to-average power ratio (PAPR) is one of the major problems of orthogonal frequency division multiplexing (OFDM) systems in wireless transmission. Therefore, partial transmit sequence (PTS), a promising scheme that can provide good PAPR reduction performance, has been proposed for OFDM transmission to eliminate distortion. The PTS method divides the input data block into disjoint s...