Heritable trait variation is a central and necessary ingredient of evolution. Trait variation also directly affects ecological processes, generating a clear link between evolutionary and ecological dynamics. Despite the changes in variation that occur through selection, drift, mutation, and recombination, current eco-evolutionary models usually fail to track how variation changes through time. ...

ECO is a method for the recursive generation, and thereby also the enumeration of classes of combinatorial objects. It has already found successful application in recent literature both to the exhaustive generation and to the uniform random generation of various objects classified according to several parameters of interest, as well as to their enumeration. In this paper we extend this approach...

The DNA coding for ribosomal RNA from Lytechinus variegatus, an Atlantic sea urchin species, is arranged in repeating units. Each unit is cleaved into four fragments by the restriction endonuclease Eco RI. The same gene region is dissected by the enzyme Sal 1 to yield two fragments. The restriction nuclease Kpn I has one restriction site within each repeat unit, thus generating a single fragmen...

This paper discusses a practical, computerised eco-management system for agriculture which has been developed at the University of Hertfordshire, UK for use by farmers and their advisers to encourage more sustainable practices. The research and software development has been funded by the UK’s Ministry of Agriculture, Fisheries and Food and the Milk Development Council. The computerised system h...

Development of a gene delivery system with high efficiency and a good safety profile is essential for successful gene therapy. Here we developed a targeted non-viral delivery system using a multifunctional lipid ECO for treating Leber's congenital amaurosis type 2 (LCA2) and tested this in a mouse model. ECO formed stable nanoparticles with plasmid DNA (pDNA) at a low amine to phosphate (N/P) r...

In this report, we present the Eco aspect-oriented framework for Java. Eco’s main goals are a flexible and open design and allowing static type-checking. Eco realizes its flexibility and openness by employing a pure and well-designed object-oriented approach. Static type-checking is realized by exploiting the novel Java generics feature. In this report, we evaluate Eco with respect to these goa...

The DNA coding for ribosomal RNA from Lytechinus variegatus, an Atlantic sea urchin species, is arranged in repeating units. Each unit is cleaved into four fragments by the restriction endonuclease Eco RI. The same gene region is dissected by the enzyme Sal 1 to yield two fragments. The restriction nuclease Kpn I has one restriction site within each repeat unit, thus generating a single fragmen...

Design of products permits to yield goods and services to produce satisfaction on customers, which is measured as value. However, it is at this stage in which most of the environmental impact, from a lifecycle perspective, is added to the product. Eco-design aims at increasing value of products while reducing the burdens on the environment by means conscious design towards efficient use of reso...