نتایج جستجو برای: 1 pyrroline 5 carboxylate synthetase p5cs

تعداد نتایج: 3385599  

2017
Priyanka Soni Malik Z. Abdin

Water stress is one of the most critical abiotic stresses that restricts growth, development, and alters physiological and biochemical mechanisms of plant. The effects of long-term water shortage-induced oxidative stress on morphophysiological parameters, proline metabolic genes, and artemisinin content were studied in Artemisia annua L. under greenhouse conditions. Plant growth, biomass accumu...

2015
Yanina S. Rizzi Mariela I. Monteoliva Georgina Fabro Carola L. Grosso Laura E. Laróvere María E. Alvarez

Plants facing adverse conditions usually alter proline (Pro) metabolism, generating changes that help restore the cellular homeostasis. These organisms synthesize Pro from glutamate (Glu) or ornithine (Orn) by two-step reactions that share Δ(1) pyrroline-5-carboxylate (P5C) as intermediate. In the catabolic process, Pro is converted back to Glu using a different pathway that involves Pro dehydr...

Journal: :Chemical communications 2012
Hiroyuki Kawai Yutaka Sugita Etsuko Tokunaga Hiroyasu Sato Motoo Shiro Norio Shibata

The first asymmetric synthesis of β-trifluoromethylated pyrroline carboxylates has been achieved by organocatalytic conjugated addition of adamantyl glycine imine to β-trifluoromethylated enones, followed by a deprotection/cyclization/dehydration sequence.

2012
Dirk Hofreuter Juliane Mohr Olga Wensel Sebastian Rademacher Kerstin Schreiber Dietmar Schomburg Beile Gao Jorge E. Galán

Campylobacter jejuni is a major cause of food-borne disease in industrialized countries. Carbohydrate utilization by C. jejuni is severely restricted, and knowledge about which substrates fuel C. jejuni infection and growth is limited. Some amino acids have been shown to serve as carbon sources both in vitro and in vivo. In the present study we investigated the contribution of serine and prolin...

Journal: :Plant physiology 2007
Elodie Parre Mohamed Ali Ghars Anne-Sophie Leprince Laurent Thiery Delphine Lefebvre Marianne Bordenave Luc Richard Christian Mazars Chedly Abdelly Arnould Savouré

Proline (Pro) accumulation occurs in various plant organisms in response to environmental stresses. To identify the signaling components involved in the regulation of Pro metabolism upon water stress in Arabidopsis (Arabidopsis thaliana), a pharmacological approach was developed. The role of phosphoinositide-specific phospholipases C (PLCs) in Pro accumulation was assessed by the use of the ami...

Journal: :The Plant cell 2014
Gang Wang Jushan Zhang Guifeng Wang Xiangyu Fan Xin Sun Hongli Qin Nan Xu Mingyu Zhong Zhenyi Qiao Yuanping Tang Rentao Song

Proline, an important amino acid, accumulates in many plant species. Besides its role in plant cell responses to environmental stresses, the potential biological functions of proline in growth and development are unclear. Here, we report cloning and functional characterization of the maize (Zea mays) classic mutant proline responding1 (pro1) gene. This gene encodes a Δ1-pyrroline-5- carboxylate...

Journal: :Biochemistry 2008
Tommi A White William H Johnson Christian P Whitman John J Tanner

The flavoenzyme proline dehydrogenase catalyzes the first step of proline catabolism, the oxidation of proline to pyrroline-5-carboxylate. Here we report the first crystal structure of an irreversibly inactivated proline dehydrogenase. The 1.9 A resolution structure of Thermus thermophilus proline dehydrogenase inactivated by the mechanism-based inhibitor N-propargylglycine shows that N5 of the...

2015
Giuseppe Forlani Kira S. Makarova Milosz Ruszkowski Michele Bertazzini Boguslaw Nocek

Proline plays a crucial role in cell growth and stress responses, and its accumulation is essential for the tolerance of adverse environmental conditions in plants. Two routes are used to biosynthesize proline in plants. The main route uses glutamate as a precursor, while in the other route proline is derived from ornithine. The terminal step of both pathways, the conversion of δ(1)-pyrroline-5...

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