Introduction: In cardiac imaging, it is essential to consider the homogeneity of the active B1 field (B1+) [1]. We present a realtime implementation of Transmit In-Plane Compensation (TIP-COMP) RF pulse [2], which can compensate different B1+ variations. Methods: Experiments were performed on a GE Signa EXCITE 3.0T system using a custom real-time imaging system [3]. To validate the accuracy of ...

We use the following convention: A, B, C, A1, B1, C1, A2, B2, C2 are points of E2 T, l1, m1, n1 are real numbers, and X, Y , Z are subsets of E2 T. Let us consider X, Y . We introduce X is parallel to Y as a synonym of X misses Y . Let us consider X, Y , Z. We say that X, Y , Z are concurrent if and only if: (Def. 1) X is parallel to Y and Y is parallel to Z and Z is parallel to X or there exis...

B1 B cells produce natural IgM and play a critical role in the early defense against bacterial and viral infection. The polyreactive IgM also contributes to the clearance of apoptotic products and plays an important role in autoimmune pathogenesis. However, the mechanism of activation and proliferation of B1 cells remains obscure. In this study, we report that IL-33, a new member of IL-1 family...

Proliferation of fibrotic tissue (desmoplasia) is one of the hallmarks of several epithelial tumors including pancreatic adenocarcinoma. This tissue reaction may be deleterious or advantageous to the host or tumor. In a systematic analysis, we identified two growth factors expressed by human pancreatic carcinoma cells that are positively correlated with the ability to induce fibroblast prolifer...

The survival of postmitotic neurons needs continuous degradation of cyclin B1, a mitotic protein accumulated aberrantly in the damaged brain areas of Alzheimer's disease and stroked patients. Degradation of cyclin B1 takes place in the proteasome after ubiquitylation by the anaphase-promoting complex/cyclosome (APC/C)-cadherin 1 (Cdh1), an E3 ubiquitin ligase that is highly active in neurons. H...

The complex process of spermatogenesis requires the expression and precise coordination of a multitude of genes. Abnormal function of such genes is frequently associated with male infertility. Among these candidates is the human BOULE gene that is a possible fundamental mediator of meiotic transition. In this study, we describe for the first time the existence of three BOULE transcript variants...

The toxicity of Fusarium proliferatum M-7176 cultured on corn (FPC) and nutritional intervention were investigated in baby chicks (New Hampshire x Single Comb White Leghorn) in three 2-wk feeding experiments. In Experiment 1, 30% FPC decreased weight gain (P < .05) and increased relative heart weight (RHW) (P < .01). Experiment 2 included a 2 x 2 factorial arrangement of FPC (0 or 30%) and Se (...

A system for the formation of an aflatoxin B1-reduced glutathione conjugate in vitro was developed, capable of yielding 80% conversion of aflatoxin B1 into the conjugate. A reverse-phase high-pressure-liquid-chromatography system was also devised that not only facilitates improved resolution of the compound but that, by manipulation of the pH, is also capable of an extensive purification of the...

The concept of semicopula plays a fundamental role in the definition of a universal integral. We present an extension of semicopula to the case of symmetric interval [−1,1]. We call this extension bipolar semicopula. The last definition can be used to obtain a simplified definition of the bipolar universal integral. Moreover bipolar semicopulas allow for extension of theory of copulas to the in...

Ephrin-B/EphB family proteins are implicated in bidirectional signaling and were initially defined through the function of their ectodomain sequences in activating EphB receptor tyrosine kinases. Ephrin-B1-3 are transmembrane proteins sharing highly conserved C-terminal cytoplasmic sequences. Here we use a soluble EphB1 ectodomain fusion protein (EphB1/Fc) to demonstrate that ephrin-B1 transduc...