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OBJECTIVE Disruptions in stress response system development have been posited as mechanisms linking child maltreatment (CM) to psychopathology. Existing theories predict elevated sympathetic nervous system reactivity after CM, but evidence for this is inconsistent. We present a novel framework for conceptualizing stress reactivity after CM that uses the biopsychosocial model of challenge and th...
Abstract Study question Are fragmentation levels (single-double stranded DNA breaks) or aneuploidy frequencies in sperm increased patients with testicular cancer who recovered spermatogenesis after chemotherapy (CT)? Summary answer Similar of and frequency are found men pre- post-chemotherapy. What is known already Testicular the most frequent solid tumor among young men. Therefore, restoration...
El objetivo del presente trabajo es presentar las evidencias de Validez Patient Health Questionnaire- 9 (PQH.9) para adultos argentinos. pqh-9 cuenta con items que permiten evaluar sintomatología Trastorno Depresivo Mayor. En el contexto local, la PQH-9 muestra propiedades psicométricas adecuadas: Indicadores confiabilidad ω .835 y α .857 apropiados índices ajuste, RMSEA: .053, CFI .99. Así tam...
An updated model of the GABA(A) benzodiazepine receptor pharmacophore of the α5-BzR/GABA(A) subtype has been constructed prompted by the synthesis of subtype selective ligands in light of the recent developments in both ligand synthesis, behavioral studies, and molecular modeling studies of the binding site itself. A number of BzR/GABA(A) α5 subtype selective compounds were synthesized, notably...
Early repolarization syndrome (ERS) is characterized by J-point elevation presenting as slurring or notching of the terminal part QRS complex. Of several congenital and acquired disorders that encompass J-wave syndromes, ERS has been linked to increased risk developing polymorphic VT idiopathic VF can lead sudden cardiac death. To describe a patient who presented after arrest with initial ECG c...
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