Systemic lupus erythematosus (SLE) is a female-biased multisystem inflammatory disease with substantial morbidity and mortality limited treatment options. Our lab previously found that VGLL3, putative transcription co-factor increased activity in female cells, can drive lupus-like systemic inflammation when overexpressed mouse epidermis under the K5 promoter. IL-7 signaling was to be elevated s...

Background. Patients with chronic coronary artery disease exhibit a dysfunctioning endothelium, which may be responsible for exercise-induced platelet activation and expression of a procoagulant moiety. In this study, we evaluated the therapeutic efficacy of a low molecular weight heparin (Parnaparin) in patients with stable angina pectoris. Methods and Results. According to a double-blind, ran...

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Maciej Wojciech Pilecki1, Małgorzata Kowal2, Agnieszka Woronkowicz2, Łukasz Kryst2, Jan Sobiecki2: 1Department of Child and Adolescent Psychiatry Jagiellonian University, Collegium Medicum, Kraków, Poland. 2School of Anthropology in the University School of Physical Education (AWF) in Kraków, Poland. Correspondence address: Maciej Pilecki, Department of Child and Adolescent Psychiatry Jagiellon...

In this paper we present a computer{assisted proof of the existence of a solution for the Feigenbaum equation '(x) = 1 '('( x)): There exist by now various such proofs in the literature. Although the one presented here is new, the main purpose of this paper is not to provide yet another version, but to give an easy{to{read and self contained introduction to the technique of computer{assisted pr...

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An architecture for a memory-resident, Parallel and Persistent ObjectSTore (PPOST) is suggested. Different object-oriented databases might be built on top of PPOST. The term memory-resident (or main memory based) means that the primary storage device is main memory. Persistence is guaranteed automatically by managing secondary and stable storage devices (such as main memory with uninterrupted p...