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BACKGROUND Clostridium difficile whole genome sequencing has the potential to identify related isolates, even among otherwise indistinguishable strains, but interpretation depends on understanding genomic variation within isolates and individuals. METHODS Serial isolates from two scenarios were whole genome sequenced. Firstly, 62 isolates from 29 timepoints from three in vitro gut models, ino...
OBJECTIVES/HYPOTHESIS This study was intended to evaluate prognostic factors and the role of postoperative radiotherapy (RT) in patients with adenoid cystic carcinoma (ACC) of the head and neck (ACCHN). STUDY DESIGN Retrospective study. METHODS Eighty-eight patients with ACCHN who underwent curative intent surgery with or without RT between 1991 and 2009 at a single institute were retrospec...
BACKGROUND Dexmedetomidine provides smooth emergence with reduced agitation. The authors hypothesized low-dose dexmedetomidine infusion might contribute to hemodynamic stability during and after nasotracheal tube extubation. METHODS Ninety-three adult patients scheduled for oral and maxillofacial surgery were enrolled in this prospective study. Patients were randomly assigned to receive norma...
Abstract Among the galactic sources that can be detected by KM3NeT detector, we will consider eHWC J1825-134 source recently HAWC telescope. Moreover, RX J1713.7-3946 and show prospects of detection in a fully hadronic lepto-hadronic scenario. Considering IceCube instead, focus on gamma-ray J1907+063 J2019+368. We found at 3 σ or more detector should within reach next decade. Finally, also 2HWC...
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