Hormonal control of human cancer was first used therapeutically by Beatson in 1895 when he reported response of a massive breast tumour after bilateral salpingo-oophorectomy. Apart from breast cancer several other tumours are now successfully treated with hormones. It has only recently been realised that gut tumours may be under hormonal control.25 Many hormones may affect the growth of gastric...

Hormonal control of human cancer was first used therapeutically by Beatson in 1895 when he reported response of a massive breast tumour after bilateral salpingo-oophorectomy. Apart from breast cancer several other tumours are now successfully treated with hormones. It has only recently been realised that gut tumours may be under hormonal control.25 Many hormones may affect the growth of gastric...

Rabies is endemic worldwide, and causes approximately 30 000 deaths per year. In the past 20 years, 12 deaths have occurred in the UK, although all but one case were contracted overseas. We have reviewed the current literature regarding the management of possible rabies exposure in the setting of a UK emergency department. The article offers an overview of rabies, including pathology, risk asse...

More than a year has passed since the first confirmed case of SARS-CoV-2 infection in US was reported on January 20, 2020 What followed an unprecedented with nearly 30 million documented infections and more 500 000 excess deaths due to Alongside this devastation is successful development deployment multiple safe effective vaccines To date, almost 80 doses vaccine have been administered some exp...

850 Bulletin of the World Health Organization 2003, 81 (11) A group of children look at Batista, a 2-year-old boy suffering from severe malnutrition at the "New Hope" refugee camp in Nabuangongo, Angola, some 20 kilometres (12 miles) north-east of Luanda. The study found that, of those surveyed, the death rate was four times higher than normal for children under the age of 5: 4.5 deaths per 10 ...

To support their argument that results of cancer screening trials based on disease-specific mortality are unreliable, Black et al. (1) compared the treatment effect measured by disease-specific mortality with the effect measured by all-cause mortality in 12 such trials. They found “major inconsistencies” between the two measures. We disagree with their interpretation and illustrate our reasons ...

OBJECTIVE To assess the impact of the adoption of evidence based guidelines on maternal mortality reduction at Enugu State University Teaching Hospital, Nigeria. MATERIALS AND METHODS A retrospective review of all maternal deaths between 1 st January, 2005 and 31 st December, 2010 was carried out. Evidence based management guidelines for eclampsia and post-partum hemorrhage were adopted. Thes...

AIMS Little is known regarding temporal trends in mortality attributed to heart failure (HF) from a population perspective. The aim of this study was to assess the mortality related to HF as an underlying cause during the last 20 years in seven European countries. METHODS AND RESULTS The number of deaths with HF as the underlying cause was collected in seven European states: Germany, Greece, ...

Introduction Cardiovascular diseases have become increasingly important as a cause of maternal death in the Nordic countries. This is likely to be associated with rising incidence pregnant women congenital and acquired cardiac diseases. Through audits, we aim prevent future deaths by identifying causes suboptimal factors clinical management. Material methods Maternal countries from 2005 2017 we...

The CVD mortality has decreased over the past 50 years at a faster pace than the OECD average, reaching the lowest in the OECD at 171 per 100 000 population, 43% lower than the OECD average of 299 (Figure 1). However, potential years of life lost, a commonly used measure of premature mortality, at 807 per 100 000 population for diseases of the circulatory system in 2011, is 39% higher than the ...