The speci cation of a real time system is often the result of a process whereby a conceptual control sys tem is eshed out as a computer program To be accu rate this process must preserve important causal and structural properties of the control system For ex ample if the control system has multiple functional components operating concurrently then the process of mapping these components into a ...

BACKGROUND AND OBJECTIVE Little information is available on the rapid diagnostic testing for syphilis in Burkina Faso. The objectives of the study were (i) to assess the sensitivity and specificity of four on site rapid tests in comparison with Treponema pallidum haemagglutination assay (TPHA) as a gold standard and (ii) to evaluate the operational characteristics of those tests among health wo...

Granulin (GRN) mutations have been identified in familial frontotemporal lobar degeneration patients with ubiquitin pathology. GRN transcript haploinsufficiency is proposed as a disease mechanism that leads to the loss of functional progranulin (PGRN) protein. Thus, these mutations are strongly involved in frontotemporal lobar degeneration pathogenesis. Moreover, recent findings indicate that G...

ELD, ELT/B1, Krebs II, and Sarcoma 180 ascites tumor cells were examined for the mitochondria! malic enzymes. The nicotinamide adenine dinucleotide (phosphate) [NAD(P) ]-dependent malic enzyme was present in all mitochondria! fractions at activities that ranged from 21 to 27 nmol reduced nicotinamide adenine dinucleotide formed per min per mg mitochondria! protein. As judged by kinetic properti...

In this paper, we aim to provide a systematic study of the relationship be-tween Chernoff information and topological, as well as algebraic propertiesof the corresponding Gaussian tree graphs for the underlying graphical test-ing problems. We first show the relationship between Chernoff informationand generalized eigenvalues of the associated covariance matrices. It is then<...

One key challenge in statistical relational learning (SRL) is scalable inference. Unfortunately, most realworld problems in SRL have expressive models that translate into large grounded networks, representing a bottleneck for any inference method and weakening its scalability. In this paper we introduce Preference Relaxation (PR), a two-stage strategy that uses the determinism present in the un...

The control of polyamine synthesis in neoplastia cells is com plex and incompletely understood. Using murine lymphoma cells deficient in methylthioadenosine (MTA) phosphorylase, we have analyzed the role of MTA in the regulation of ornithine decarboxylase and S-adenosylmethionine (SAM) decarboxylase, the two rate-limiting enzymes in the polyamine-biosynthetic pathway. The addition of MTA to the...

Introduction: The image quality as well as film speed is influenced by the film processing conditions. Different combinations of films and processing methods affect the diagnostic accu-racy. Temperature and developer exhaustion result in different image quality. The purpose of this study was to evaluate the influence of film type and processing conditions on caries detec-tion. &nbsp;Material a...

The emergence of Linked Open Data (LOD) enables data on the Web to have a well defined structure and thereby to represent and in‐ terlink information from different sources and application areas. This web of data is a complex socially created network, where concepts and rela‐ tions are connected in intricate ways, collectively forming a network of knowledge. These data are published in a decent...

BACKGROUND Accurate and reliable blood glucose (BG) measurements require that different test strip lots of the same BG monitoring system provide comparable measurement results. Only a small number of studies addressing this question have been published. METHODS In this study, four test strip lots for each of five different BG systems [Accu-Chek® Aviva (system A), FreeStyle Lite® (system B), G...