Checkpointing is a fault-tolerance mechanism commonly used in High Throughput Computing (HTC) environments to allow the execution of long-running computational tasks on compute resources subject to hardware or software failures as well as interruptions from resource owners and more important tasks. Until recently many researchers have focused on the performance gains achieved through checkpoint...

To assist the bioinformatic community in leveraging the national cyberinfrastructure, the National Center for Genomic Analysis Support (NCGAS) along with Indiana University's High Throughput Computing (HTC) group have engineered a method to use the Galaxy to submit BLAST jobs to the Open Science Grid (OSG). OSG is a collaboration of resource providers that utilize opportunistic cycles at more t...

Reproducible induction of the enzyme tyrosine aminotransferase by dibutyryl cAMP (Bt2cAMP) in a line of HTC hepatoma cells in suspension culture requires that the cells be preinduced with dexamethasone, a synthetic glucocorticoid which itself induces tyrosine aminotransferase. Concentrations of dexamethasone that do not induce tyrosine aminotransferase fail to support Bt2cAMP induction, removal...

HTC rat hepatoma cells were transfected with human insulin receptor cDNA to a level of 40,000 receptors/cell. In these cells, as well as in nontransfected cells, insulin stimulated the uptake of alpha-aminoisobutyric acid. Two monoclonal antibodies directed against the human insulin receptor alpha subunit, like insulin, stimulated amino acid uptake in transfected HTC cells, but not in nontransf...

Checkpointing is a fault-tolerance mechanism commonly used in High Throughput Computing (HTC) environments to allow the execution of long-running computational tasks on compute resources subject to hardware and software failures and interruptions from resource owners. With increasing scrutiny of the energy consumption of IT infrastructures, it is important to understand the impact of checkpoint...

OBJECTIVE To investigate whether community engagement (participation in grassroots organizations) contributed to increases in HIV testing in Zimbabwe. METHODS Prospective data on membership of local community organizations (e.g. women's groups and burial societies) and uptake of HIV testing and counselling (HTC) and prevention-of-mother-to-child transmission (PMTCT) services were collected fr...