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تعداد نتایج: 89179 فیلتر نتایج به سال:
The global financial crisis began with a financial meltdown in the United States in early 2008 and then it had spread to the rest of the world. In this paper we test whether the MENA equity market volatility presents a different behavior before and after the financial crisis of 2008. Using long range dependence techniques we test for long memory in the returns, absolute and squared returns of t...
Noncommunicable diseases (NCDs) are a major and increasing global health issue. The World Health Organization (WHO) estimates that NCDs represent 63% of all global deaths of which 3.9 million are due to chronic respiratory diseases (CRDs) and Chronic Obstructive Pulmonary Disease (COPD) in particular. COPD is now the third most common cause of death globally; 90% of these deaths occur in Low an...
Filamin c is the predominantly expressed filamin isoform in striated muscles. It is localized in myofibrillar Z-discs, where it binds FATZ and myotilin, and in myotendinous junctions and intercalated discs. Here, we identify Xin, the protein encoded by the human gene 'cardiomyopathy associated 1' (CMYA1) as filamin c binding partner at these specialized structures where the ends of myofibrils a...
Functional interactions between classical cadherins and the actin cytoskeleton involve diverse actin activities, including filament nucleation, cross-linking, and bundling. In this report, we explored the capacity of Ena/VASP proteins to regulate the actin cytoskeleton at cadherin-adhesive contacts. We extended the observation that Ena/vasodilator-stimulated phosphoprotein (VASP) proteins local...
خلیج فارس در سده اخیر ، بدون تردید یکی از مهم ترین و حساس ترین مناطق جهان در نگرش های ژئواستراتژیک بوده است لذا در آغاز قرن 21 به عنوان مهم ترین کانون تحولات منطقه ای مورد توجه قرار گرفته و به تعبیر کلاسیک ژئوپلتیک ها ، هارتلند یا قلب زمین ، نامیده شده است اهمیت منطقه خلیج فارس به عنوان یک منطقه حساس جغرافیایی و ژئوپلتیکی جهان برای هیچ تحلیل گر و صاحب نظر مسائل بین المللی پوشیده نیست و به این ل...
The relationship between institutions and economic growth is one of the main issues in economic development debates and has been considered empirically in recent years. Hence, the main purpose of this paper is to investigate the effects of institutions and recourses management improvement on economic growth in MENA countries during the period of 1996-2018. For achieving this, the econometric mo...
Abstract How do White Americans evaluate the politics of belonging in United States across different ethnoreligious identity categories? This paper examines this question through two competing frameworks. On one hand, given salience anti-Muslim attitudes States, we consider whether penalize Muslim immigrants to regardless their ethnoracial background. other is often conflated by general public ...
تغییر در میزان باروری،به عنوان یکی از عوامل موثر بر تغییرات جمعیتی و نقش آن در عرضه نیروی کار و در نتیجه رشد تولید، عنصر مهم رشد و توسعه اقتصادی- اجتماعی هر کشور تلقی میشود. اهمیت تغییرات جمعیتی درهر کشور تا حدی است که در سالهای اخیر، پیری جمعیت در حالت کلی و بهویژه کاهش باروری، نگرانیهایی را برای اقتصاد در سطح جهانی و اکثر جوامع درحالتوسعه از جمله ایران ایجاد کردهاست. این در حالی است که ...
BACKGROUND Pompe disease is a rare autosomal recessive disorder caused by a deficiency of the lysosomal enzyme alpha-glucosidase responsible for degrading glycogen. Late-onset Pompe disease has a complex multisystem phenotype characterized by a range of symptoms. METHODS An expert panel from the Middle East and North Africa (MENA) region met to create consensus-based guidelines for the diagno...
FE65 binds to the Alzheimer amyloid precursor protein (APP), but the function of this interaction has not been identified. Here, we report that APP and FE65 are involved in regulation of cell movement. APP and FE65 colocalize with actin and Mena, an Abl-associated signaling protein thought to regulate actin dynamics, in lamellipodia. APP and FE65 specifically concentrate with beta 1-integrin in...
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