The techniques and measurement methods developed in the Environmental Survey and Monitoring of Chemicals by Japan's Ministry of the Environment, as well as a large amount of knowledge archived in the survey, have led to the advancement of environmental analysis. Recently, technologies such as non-target liquid chromatography/high resolution mass spectrometry and liquid chromatography with micro...

We examined young adult and late middle-aged male rats to test the hypothesis that gastrocnemius (a locomotor muscle) demonstrates reduced fiber size with aging, whereas soleus (a postural muscle) demonstrates atrophy of some fibers and compensatory hypertrophy in other fibers. Although body mass was greater in late middle-aged animals, mass was reduced in gastrocnemius but not soleus muscle. I...

In order to fully characterize the performance of the colloid thruster system the electrospray (ES) beam must itself be fully characterized. This may be achieved by measuring various properties such as flow rate, current, droplet/ion charge to mass ratio and current profile. Beam properties of both standard electrospray mass spectrometry (ESMS) emitters and arrays of custom made micro-fabricate...

Upcoming γ-ray satellites will search for Dark Matter annihilations in Milky Way substructures (or ’clumps’). The prospects for detecting these objects strongly depend on the assumptions made on the distribution of Dark Matter in substructures, and on the distribution of substructures in the Milky Way halo. By adopting extreme prescriptions for these quantities, we bracket the number of sources...

The paper investigates the fabrication of Selective Laser Melting (SLM) titanium alloy Ti6Al4V micro-lattice structures for the production of lightweight components. Specifically, the pillar textile unit cell is used as base lattice structure and alternative lattice topologies including reinforcing vertical bars are also considered. Detailed characterizations of dimensional accuracy, surface ro...

A fundamental challenge in the drug discovery process is to develop compounds with high efficacy and minimal side-effects. We describe a new approach to proteome-wide drug screening for detection of on- and off-target binding which combines the advantages of mass spectrometry with microarray technology. The method involves matrix-assisted laser desorption/ionization mass spectrometric imaging (...