Aim: Mesenchymal stem cells can easily differentiate into cardiomyocytes in vitro conditions using various protocols. However, the agents used these protocols have been reported to some adverse effects on cell viability. Azacitidine is mesenchymal cardiac muscle cells. The aim of present study was investigate Exenatide a GLP-1 receptor agonist, differentiation and viability human adipose tissue...

Background: Hypertrophic Cardiomyopathy (HCM) is one of the leading causes sudden cardiac death in adults.HCM inherited an autosomal dominant manner; however, genetic etiology disease not fully explained and studies on hereditary characteristics family trees are still underway. Methods: Ten HCM patients 31 their relatives were recruited. Targeted sequencing for 4 related-genes, including MYH7 ,...

The dynamic migratory behavior of human mesenchymal stem cells (hMSCs) has a significant impact on the epigenetic profiles that determine fate choice and lineage commitment during differentiation. Here we report novel approach to enhance repeated migration-driven memory which induces cardiomyogenic differentiation dendrimer surface with fifth generation (G5). Cells exhibited formation cell aggr...