نتایج جستجو برای: ژن mec a
تعداد نتایج: 13445811 فیلتر نتایج به سال:
On the basis of synthetic lethality, five genes in Caenorhabditis elegans are known to be redundant with the mec-8 gene, which encodes a protein that contains two copies of an RNA recognition motif (RRM) and affects alternative RNA splicing. The molecular identities of two of the redundant genes, sym-1 and sym-5, were previously reported. The remaining three genes have now been cloned, and thei...
The hippocampus is a brain region that is critical for spatial learning, context-dependent memory, and episodic memory. It receives major inputs from the medial entorhinal cortex (MEC) and the lateral EC (LEC). MEC neurons show much greater spatial firing than LEC neurons in a recording chamber with a single, salient landmark. The MEC cells are thought to derive their spatial tuning through pat...
The production of a basal lamina by microvascular endothelial cells (MEC) cultured on various substrata was examined. MEC were isolated from human dermis and plated on plastic dishes coated with fibronectin, or cell-free extracellular matrices elaborated by fibroblasts, smooth muscle cells, corneal endothelial cells, or PF HR9 endodermal cells. Examination of cultures by electron microscopy at ...
The methylation of cytosine to 5-methylcytosine (5-meC) is an important epigenetic DNA modification in many bacteria, plants, and mammals, but its relevance for important model organisms, including Caenorhabditis elegans and Drosophila melanogaster, is still equivocal. By reporting the presence of 5-meC in a broad variety of wild, laboratory, and industrial yeasts, a recent study also challenge...
Abstract A synthetic cathinone called 4-methylethcathinone (4-MEC) emerged online in 2010, and was cyber-marketed to be a replacement for mephedrone. The study aimed to present user experiences of 4-MEC as reported on the Internet, with a focus on user profiles, sourcing and product characteristics, routes of administration, dosage, positive and undesirable effects, and comparisons to mephedron...
37 38 Hippocampal neurons show a strong modulation by theta frequency oscillations. 39 This modulation is thought to be important for temporal encoding and decoding of 40 information in the hippocampal system, as well as for temporal ordering of neuronal 41 activities on time scales at which physiological mechanisms of synaptic plasticity 42 operate. The medial entorhinal cortex (MEC), one of t...
All organisms sense their immediate environment using specialized mechanoreceptors, cells that respond to external mechanical forces. These exquisitely sensitive cells underlie osmosensation, touch, hearing, balance and proprioception. All mechanoreceptors that have been studied in depth respond to external forces by opening transduction channels — mechanically gated ion channels. Although larg...
Previous work has shown that C. elegans MEC-8 is a putative RNA-binding protein that promotes specific alternative splices of unc-52 transcripts. unc-52 encodes homologs of mammalian perlecan that are located extracellularly between muscle and hypodermis and are essential for muscle development in both embryos and larvae. We show that MEC-8 is a nuclear protein found in hypodermis at most stage...
For any software company that frequently performs quality assurance activities devoted to measurement, evaluation (ME) and change/improvement (MEC) projects, ME and MEC strategies can be valuable organizational assets. In this paper, we analyze the improvement of a ME strategy, which can be considered an organizational resource to be applied to quality assurance activities. This resource is cal...
BACKGROUND The term meningoencephalocele (MEC) describes a herniation of cerebral tissue and meninges through a defect in the cranium, whereas a meningocele (MC) is a herniation of the meninges alone. HYPOTHESIS/OBJECTIVES To describe the clinical features, magnetic resonance imaging (MRI) characteristics, and outcomes of dogs with cranial MC and MEC. ANIMALS Twenty-two client-owned dogs di...
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